# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA559147 | Y-27632 | Activity | = | -32 | mmHg | ALA5236758 | mmHg | Rattus norvegicus | |||
2. | ALA559147 | Y-27632 | Activity | = | -10 | mmHg | ALA5236757 | mmHg | Rattus norvegicus | |||
3. | ALA559147 | Y-27632 | Activity | = | 75 | bpm | ALA5236753 | bpm | Rattus norvegicus | |||
4. | ALA559147 | Y-27632 | Activity | = | -5 | mmHg | ALA5236752 | mmHg | Rattus norvegicus | |||
5. | ALA559147 | Y-27632 | Activity | = | -10 | mmHg | ALA5236751 | mmHg | Rattus norvegicus | |||
6. | ALA559147 | Y-27632 | Activity | = | -25 | mmHg | ALA5236750 | mmHg | Rattus norvegicus | |||
7. | ALA559147 | Y-27632 | Activity | = | 0 | bpm | ALA5236749 | bpm | Rattus norvegicus | |||
8. | ALA559147 | Y-27632 | Activity | = | 10 | bpm | ALA5236747 | bpm | Rattus norvegicus | |||
9. | ALA559147 | Y-27632 | IC50 | = | 30 | uM | ALA5236743 | 4.52 | nM | Homo sapiens | ||
10. | ALA559147 | Y-27632 | IC50 | = | 1.4 | uM | ALA5236741 | 5.85 | nM | Homo sapiens | ||
11. | ALA559147 | Y-27632 | Ki | = | 300 | nM | ALA5150293 | 6.52 | nM | Homo sapiens | ||
12. | ALA559147 | Y-27632 | Ki | = | 140 | nM | ALA5150292 | 6.85 | nM | Homo sapiens | ||
13. | ALA559147 | Y-27632 | logP | = | 0.62 | ALA5136855 | ||||||
14. | ALA559147 | Y-27632 | logD | = | 1.03 | ALA5136854 | ||||||
15. | ALA559147 | Y-27632 | Kinetic_solubility | 0 | ALA5136853 | ND | ||||||
16. | ALA559147 | Y-27632 | IC50 | = | 3.026 | uM | ALA5136852 | 5.52 | nM | |||
17. | ALA559147 | Y-27632 | IC50 | = | 0.143 | uM | ALA5136851 | 6.84 | nM | Homo sapiens | ||
18. | ALA559147 | Y-27632 | inhibition | = | 4.1 | % | ALA4808150 | % | Homo sapiens | |||
19. | ALA559147 | Y-27632 | inhibition | = | 38.63 | % | ALA4808149 | % | Homo sapiens | |||
20. | ALA559147 | Y-27632 | Inhibition | = | -6.37 | % | ALA4303805 | % | Severe acute respiratory syndrome coronavirus 2 |