# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA574646 | 2, EF31 | IC50 | = | 0.95 | uM | ALA4324157 | 6.02 | nM | Homo sapiens | ||
2. | ALA574646 | 2, EF31 | DIZ | = | 4.7 | mm | ALA3412343 | mm | Mycobacterium marinum | |||
3. | ALA574646 | 2, EF31 | Tmax | = | 15 | min | ALA3413275 | hr | Mus musculus | |||
4. | ALA574646 | 2, EF31 | Cmax | = | 1067 | ng/ml | ALA3413279 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
5. | ALA574646 | 2, EF31 | t1/2 | = | 132 | min | ALA3413283 | hr | Mus musculus | |||
6. | ALA574646 | 2, EF31 | AUC | = | 622286 | nM.min | ALA3413287 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
7. | ALA574646 | 2, EF31 | AUC | = | 2876 | nM.min | ALA3413287 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
8. | ALA574646 | 2, EF31 | Activity | 0 | ALA3398744 | Non-toxic | ||||||
9. | ALA574646 | 2, EF31 | INH | 0 | ALA3398743 | Active | % | Homo sapiens | ||||
10. | ALA574646 | 2, EF31 | INH | = | 57.9 | % | ALA3398741 | % | Homo sapiens | |||
11. | ALA574646 | 2, EF31 | INH | = | 73.2 | % | ALA3398740 | % | ||||
12. | ALA574646 | 2, EF31 | Activity | = | 88.1 | umol/L | ALA3398739 | umol/L | ||||
13. | ALA574646 | 2, EF31 | Activity | = | 209.2 | umol/L | ALA3398738 | umol/L | ||||
14. | ALA574646 | 2, EF31 | Ratio IC50 | = | 11.2 | ALA3398737 | ||||||
15. | ALA574646 | 2, EF31 | IC50 | = | 1 | uM | ALA3398736 | 6.00 | nM | Mus musculus | ||
16. | ALA574646 | 2, EF31 | IC50 | = | 0.2 | uM | ALA3398735 | 6.70 | nM | Homo sapiens | ||
17. | ALA574646 | 2, EF31 | IC50 | = | 1.9 | uM | ALA3398734 | 5.72 | nM | Homo sapiens | ||
18. | ALA574646 | 2, EF31 | beta t1/2 | <= | 1 | min | ALA3265867 | hr | Mus musculus | |||
19. | ALA574646 | 2, EF31 | INH | = | 107 | % | ALA2342698 | % | Homo sapiens | |||
20. | ALA574646 | 2, EF31 | INH | = | 107 | % | ALA2342697 | % | Homo sapiens |