# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA577478 | 10 | Vd | = | 1.3 | L/Kg | ALA1048935 | L.kg-1 | Rattus norvegicus | |||
2. | ALA577478 | 10 | CL | = | 18 | ml/min.kg | ALA1048934 | mL.min-1.kg-1 | Rattus norvegicus | |||
3. | ALA577478 | 10 | F | = | 99 | % | ALA1048933 | % | Rattus norvegicus | |||
4. | ALA577478 | 10 | PD50 | = | 21 | mg kg-1 | ALA1048932 | mg kg-1 | Streptococcus pneumoniae | |||
5. | ALA577478 | 10 | PD50 | = | 24 | mg kg-1 | ALA1048931 | mg kg-1 | Streptococcus pyogenes | |||
6. | ALA577478 | 10 | MIC | = | 0.125 | ug ml-1 | ALA1048927 | ug.mL-1 | Streptococcus pneumoniae | |||
7. | ALA577478 | 10 | MIC | = | 0.125 | ug ml-1 | ALA1048926 | ug.mL-1 | Streptococcus pneumoniae | |||
8. | ALA577478 | 10 | MIC | = | 0.5 | ug ml-1 | ALA1046303 | ug.mL-1 | Streptococcus pyogenes | |||
9. | ALA577478 | 10 | MIC | = | 0.5 | ug ml-1 | ALA1046302 | ug.mL-1 | Staphylococcus aureus | |||
10. | ALA577478 | 10 | MIC | = | 0.5 | ug ml-1 | ALA1046301 | ug.mL-1 | Staphylococcus aureus | |||
11. | ALA577478 | 10 | IC50 | = | 0.25 | uM | ALA1046300 | 6.60 | nM | Streptococcus pneumoniae | ||
12. | ALA577478 | 10 | IC50 | = | 0.053 | uM | ALA1046299 | 7.28 | nM | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) |