# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA569434 | 7b, anomeric mixture | IC50 | = | 25 | nM | ALA1040741 | 7.60 | nM | Homo sapiens | ||
2. | ALA569434 | 7b, anomeric mixture | IC50 | = | 7.1 | nM | ALA1040740 | 8.15 | nM | Mus musculus | ||
3. | ALA569434 | 7b, anomeric mixture | Vdss | = | 2.93 | L/Kg | ALA1040766 | L.kg-1 | Mus musculus | |||
4. | ALA569434 | 7b, anomeric mixture | Vdss | = | 1.98 | L/Kg | ALA1040766 | L.kg-1 | Mus musculus | |||
5. | ALA569434 | 7b, anomeric mixture | MRT | = | 1.77 | hr | ALA1040765 | hr | Mus musculus | |||
6. | ALA569434 | 7b, anomeric mixture | MRT | = | 1.62 | hr | ALA1040765 | hr | Mus musculus | |||
7. | ALA569434 | 7b, anomeric mixture | CL | = | 27.65 | ml/min.kg | ALA1040764 | mL.min-1.kg-1 | Mus musculus | |||
8. | ALA569434 | 7b, anomeric mixture | CL | = | 22.49 | ml/min.kg | ALA1040764 | mL.min-1.kg-1 | Mus musculus | |||
9. | ALA569434 | 7b, anomeric mixture | Vc/F | = | 3.08 | L/Kg | ALA1040763 | L.kg-1 | Mus musculus | |||
10. | ALA569434 | 7b, anomeric mixture | Vc/F | = | 1.91 | L/Kg | ALA1040763 | L.kg-1 | Mus musculus | |||
11. | ALA569434 | 7b, anomeric mixture | AUC | = | 1481 | nM.hr | ALA1040762 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
12. | ALA569434 | 7b, anomeric mixture | AUC | = | 1910 | nM.hr | ALA1040762 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Mus musculus | ||
13. | ALA569434 | 7b, anomeric mixture | Tmax | = | 0.25 | hr | ALA1040761 | hr | Mus musculus | |||
14. | ALA569434 | 7b, anomeric mixture | Tmax | = | 0.38 | hr | ALA1040761 | hr | Mus musculus | |||
15. | ALA569434 | 7b, anomeric mixture | t1/2 | = | 1.29 | hr | ALA1040760 | hr | Mus musculus | |||
16. | ALA569434 | 7b, anomeric mixture | t1/2 | = | 1.07 | hr | ALA1040760 | hr | Mus musculus | |||
17. | ALA569434 | 7b, anomeric mixture | F | = | 100 | % | ALA1040759 | % | Mus musculus | |||
18. | ALA569434 | 7b, anomeric mixture | F | = | 61.2 | % | ALA1040759 | % | Mus musculus | |||
19. | ALA569434 | 7b, anomeric mixture | MRT | = | 8.44 | hr | ALA1040758 | hr | Mus musculus | |||
20. | ALA569434 | 7b, anomeric mixture | MRT | = | 4.6 | hr | ALA1040758 | hr | Mus musculus |