# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA571581 | 6b | Ratio IC50 | = | 61 | ALA1047185 | ||||||
2. | ALA571581 | 6b | IC50 | = | 17 | nM | ALA1047184 | 7.77 | nM | Homo sapiens | ||
3. | ALA571581 | 6b | IC50 | = | 0.28 | nM | ALA1047183 | 9.55 | nM | Homo sapiens | ||
4. | ALA571581 | 6b | IC50 | > | 10 | uM | ALA1047204 | nM | Homo sapiens | |||
5. | ALA571581 | 6b | IC50 | > | 10 | uM | ALA1047205 | nM | Homo sapiens | |||
6. | ALA571581 | 6b | IC50 | > | 10 | uM | ALA1047206 | nM | Homo sapiens | |||
7. | ALA571581 | 6b | IC50 | > | 10 | uM | ALA1047207 | nM | Homo sapiens | |||
8. | ALA571581 | 6b | IC50 | > | 10 | uM | ALA1047208 | nM | Homo sapiens | |||
9. | ALA571581 | 6b | IC50 | = | 880 | nM | ALA1047192 | 6.06 | nM | Mus musculus | ||
10. | ALA571581 | 6b | IC50 | = | 21 | nM | ALA1047191 | 7.68 | nM | Mus musculus | ||
11. | ALA571581 | 6b | Ratio IC50 | = | 1000 | ALA1049808 | ||||||
12. | ALA571581 | 6b | Ratio IC50 | = | 1000 | ALA1049807 | ||||||
13. | ALA571581 | 6b | IC50 | = | 0.26 | uM | ALA1049806 | 6.58 | nM | Homo sapiens | ||
14. | ALA571581 | 6b | IC50 | = | 0.73 | uM | ALA1049805 | 6.14 | nM | Homo sapiens | ||
15. | ALA571581 | 6b | AUC | = | 1140 | ng.hr/ml | ALA1048055 | ng.hr.mL-1 | Rattus norvegicus | |||
16. | ALA571581 | 6b | F | = | 35 | % | ALA1048056 | % | Rattus norvegicus | |||
17. | ALA571581 | 6b | AUC | = | 1140 | ng.hr/ml | ALA1048057 | ng.hr.mL-1 | Rattus norvegicus | |||
18. | ALA571581 | 6b | Cmax | = | 108 | ng/ml | ALA1048054 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
19. | ALA571581 | 6b | Vd | = | 7.3 | L/Kg | ALA1048053 | L.kg-1 | Rattus norvegicus | |||
20. | ALA571581 | 6b | CL | = | 55 | ml/min.kg | ALA1047210 | mL.min-1.kg-1 | Rattus norvegicus |