# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA568933 | 1, enantiomer | IC50 | = | 2 | nM | ALA1837501 | 8.70 | nM | Homo sapiens | ||
2. | ALA568933 | 1, enantiomer | ED50 | = | 9.8 | nM | ALA1837502 | 8.01 | nM | Homo sapiens | ||
3. | ALA568933 | 1, enantiomer | IC50 | = | 879 | nM | ALA1837503 | 6.06 | nM | Homo sapiens | ||
4. | ALA568933 | 1, enantiomer | Ratio IC50 | = | 90 | ALA1837504 | Homo sapiens | |||||
5. | ALA568933 | 1, enantiomer | Stability | = | 16 | % | ALA1837505 | % | Mus musculus | |||
6. | ALA568933 | 1, enantiomer | Stability | = | 46 | % | ALA1837506 | % | Homo sapiens | |||
7. | ALA568933 | 1, enantiomer | Activity | = | 36 | % | ALA1837507 | % | Mus musculus | |||
8. | ALA568933 | 1, enantiomer | F | = | 2 | % | ALA1837508 | % | Mus musculus | |||
9. | ALA568933 | 1, enantiomer | CL | = | 2200 | ml/kg/hr | ALA1837509 | mL.min-1.kg-1 | Mus musculus | |||
10. | ALA568933 | 1, enantiomer | CL | = | 2200 | ml/kg/hr | ALA1112567 | mL.min-1.kg-1 | Rattus norvegicus | |||
11. | ALA568933 | 1, enantiomer | Activity | = | 36 | % | ALA1112570 | % | Mus musculus | |||
12. | ALA568933 | 1, enantiomer | Drug uptake | = | 86 | nM | ALA1112569 | nM | Mus musculus | |||
13. | ALA568933 | 1, enantiomer | Cp | = | 194 | nM | ALA1112568 | nM | Mus musculus | |||
14. | ALA568933 | 1, enantiomer | F | = | 2 | % | ALA1112566 | % | Rattus norvegicus | |||
15. | ALA568933 | 1, enantiomer | IC50 | = | 4 | nM | ALA1112565 | 8.40 | nM | |||
16. | ALA568933 | 1, enantiomer | IC50 | = | 2 | nM | ALA1037933 | 8.70 | nM | Homo sapiens | ||
17. | ALA568933 | 1, enantiomer | Stability | = | 15 | % | ALA1037934 | % | ||||
18. | ALA568933 | 1, enantiomer | Stability | = | 48 | % | ALA1037935 | % | Homo sapiens | |||
19. | ALA568933 | 1, enantiomer | Stability | = | 0 | % | ALA1037936 | % | Homo sapiens | |||
20. | ALA568933 | 1, enantiomer | Stability | = | 5 | % | ALA1037937 | % |