| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA572098 | 1 | IC50 | = | 25 | nM | ALA2321456 | 7.60 | nM | Mus musculus | ||
| 2. | ALA572098 | 1 | IC50 | = | 39 | nM | ALA2321455 | 7.41 | nM | Homo sapiens | ||
| 3. | ALA572098 | 1 | Papp | = | 24 | ucm/s | ALA2321450 | ucm/s | Homo sapiens | |||
| 4. | ALA572098 | 1 | Stability | = | 76 | % | ALA2321448 | % | Rattus norvegicus | |||
| 5. | ALA572098 | 1 | Papp | = | 22 | ucm/s | ALA2321447 | ucm/s | Homo sapiens | |||
| 6. | ALA572098 | 1 | INH | 0 | ALA2320320 | Not Active | % | Rattus norvegicus | ||||
| 7. | ALA572098 | 1 | INH | 0 | ALA2320319 | Not Active | % | Rattus norvegicus | ||||
| 8. | ALA572098 | 1 | INH | > | 60 | % | ALA2321446 | % | Rattus norvegicus | |||
| 9. | ALA572098 | 1 | t1/2 | = | 1 | hr | ALA2321443 | hr | Rattus norvegicus | |||
| 10. | ALA572098 | 1 | AUC | = | 220 | uM.hr | ALA2321442 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 11. | ALA572098 | 1 | Vdss | = | 2.2 | L/Kg | ALA2321441 | L.kg-1 | Rattus norvegicus | |||
| 12. | ALA572098 | 1 | CL | = | 1.9 | L/hr/kg | ALA2321440 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 13. | ALA572098 | 1 | Cmax | = | 0.9 | uM | ALA2321434 | nM | Rattus norvegicus | |||
| 14. | ALA572098 | 1 | Tmax | = | 1 | hr | ALA2321435 | hr | Rattus norvegicus | |||
| 15. | ALA572098 | 1 | AUC | = | 167 | uM.hr | ALA2321433 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | Rattus norvegicus | ||
| 16. | ALA572098 | 1 | F | = | 46 | % | ALA2321432 | % | Rattus norvegicus | |||
| 17. | ALA572098 | 1 | IC50 | = | 322 | nM | ALA1072554 | 6.49 | nM | Rattus norvegicus | ||
| 18. | ALA572098 | 1 | Stability | = | 42 | % | ALA1037262 | % | Rattus norvegicus | |||
| 19. | ALA572098 | 1 | IC50 | = | 0.3 | uM | ALA1041718 | 6.52 | nM | Rattus norvegicus |
The page will load shortly, Thanks for your patience!