# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA598279 | GNF-Pf-3570 | Ratio | = | 1.093 | ALA2448810 | Plasmodium falciparum | |||||
2. | ALA598279 | GNF-Pf-3570 | Motility | 0 | ALA2363031 | No effect | Schistosoma mansoni | |||||
3. | ALA598279 | GNF-Pf-3570 | Motility | = | 105.7 | ALA2363030 | No effect | Schistosoma mansoni | ||||
4. | ALA598279 | GNF-Pf-3570 | Motility | = | 100 | ALA2363029 | No effect | Schistosoma mansoni | ||||
5. | ALA598279 | GNF-Pf-3570 | Toxicity | = | 0 | ALA2363028 | No effect | Schistosoma mansoni | ||||
6. | ALA598279 | GNF-Pf-3570 | Toxicity | = | 0 | ALA2363027 | No effect | Schistosoma mansoni | ||||
7. | ALA598279 | GNF-Pf-3570 | Toxicity | = | 0 | ALA2363026 | No effect | Schistosoma mansoni | ||||
8. | ALA598279 | GNF-Pf-3570 | Toxicity | = | 4 | ALA2363025 | Dead | Schistosoma mansoni | ||||
9. | ALA598279 | GNF-Pf-3570 | Toxicity | = | 4 | ALA2363024 | Round, degenerate, slow | Schistosoma mansoni | ||||
10. | ALA598279 | GNF-Pf-3570 | Toxicity | = | 2 | ALA2363023 | Round, overactive | Schistosoma mansoni | ||||
11. | ALA598279 | GNF-Pf-3570 | Inhibition | = | 98 | % | ALA2094262 | % | Mycobacterium tuberculosis | |||
12. | ALA598279 | GNF-Pf-3570 | Inhibition | = | 53.9 | % | ALA2094261 | % | Mycobacterium tuberculosis | |||
13. | ALA598279 | GNF-Pf-3570 | LD50 | = | 2.59 | uM | ALA2094265 | uM | Homo sapiens | |||
14. | ALA598279 | GNF-Pf-3570 | MIC90 | = | 7.33 | uM | ALA2094264 | nM | Mycobacterium tuberculosis | |||
15. | ALA598279 | GNF-Pf-3570 | MIC90 | = | 48.7 | uM | ALA2094263 | nM | Mycobacterium tuberculosis | |||
16. | ALA598279 | GNF-Pf-3570 | IC50 | = | 4.028 | uM | ALA2028075 | 5.39 | nM | Trypanosoma brucei rhodesiense | ||
17. | ALA598279 | GNF-Pf-3570 | IC50 | = | 3.836 | uM | ALA2028074 | 5.42 | nM | Trypanosoma brucei brucei | ||
18. | ALA598279 | GNF-Pf-3570 | IC50 | = | 3.552 | uM | ALA2028073 | 5.45 | nM | Trypanosoma cruzi | ||
19. | ALA598279 | GNF-Pf-3570 | EC50 | = | 589 | nM | ALA2028071 | 6.23 | nM | Plasmodium falciparum | ||
20. | ALA598279 | GNF-Pf-3570 | IC50 | = | 12.382 | uM | ALA2028077 | 4.91 | nM | Homo sapiens |