Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA600132	GNF-Pf-34	Ratio	=	1.994		ALA2448810				Plasmodium falciparum
2.	ALA600132	GNF-Pf-34	Motility		0		ALA2363031		No effect		Schistosoma mansoni
3.	ALA600132	GNF-Pf-34	Motility	=	120		ALA2363030		No effect		Schistosoma mansoni
4.	ALA600132	GNF-Pf-34	Motility	=	140		ALA2363029		No effect		Schistosoma mansoni
5.	ALA600132	GNF-Pf-34	Toxicity	=	0		ALA2363028		No effect		Schistosoma mansoni
6.	ALA600132	GNF-Pf-34	Toxicity	=	0		ALA2363027		No effect		Schistosoma mansoni
7.	ALA600132	GNF-Pf-34	Toxicity	=	0		ALA2363026		No effect		Schistosoma mansoni
8.	ALA600132	GNF-Pf-34	Toxicity	=	4		ALA2363025		Dead		Schistosoma mansoni
9.	ALA600132	GNF-Pf-34	Toxicity	=	4		ALA2363024		Round, degenerate		Schistosoma mansoni
10.	ALA600132	GNF-Pf-34	Toxicity	=	0		ALA2363023		No effect		Schistosoma mansoni
11.	ALA600132	GNF-Pf-34	Inhibition	=	11.3	%	ALA2094262			%	Mycobacterium tuberculosis
12.	ALA600132	GNF-Pf-34	Inhibition	=	26.7	%	ALA2094261			%	Mycobacterium tuberculosis
13.	ALA600132	GNF-Pf-34	IC50	=	6.638	uM	ALA2028075	5.18		nM	Trypanosoma brucei rhodesiense
14.	ALA600132	GNF-Pf-34	IC50	=	12.936	uM	ALA2028074	4.89		nM	Trypanosoma brucei brucei
15.	ALA600132	GNF-Pf-34	IC50	=	3.588	uM	ALA2028073	5.45		nM	Trypanosoma cruzi
16.	ALA600132	GNF-Pf-34	EC50	=	1040	nM	ALA2028071	5.98		nM	Plasmodium falciparum
17.	ALA600132	GNF-Pf-34	IC50	>	32	uM	ALA2028077			nM	Homo sapiens
18.	ALA600132	GNF-Pf-34	IC50	=	4.028	uM	ALA2028076	5.39		nM	Leishmania infantum
19.	ALA600132	GNF-Pf-34	IC50	=	732.5	nM	ALA3392923	6.13		nM	Plasmodium falciparum
20.	ALA600132	GNF-Pf-34	IC50	>	1	uM	ALA3301567			nM	Plasmodium falciparum (isolate 3D7)