# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA582072 | GNF-Pf-3264 | Ratio | = | 1.143 | ALA2448810 | Plasmodium falciparum | |||||
2. | ALA582072 | GNF-Pf-3264 | Toxicity | = | 2 | ALA2363025 | Round, dark | Schistosoma mansoni | ||||
3. | ALA582072 | GNF-Pf-3264 | Toxicity | = | 0 | ALA2363024 | No effect | Schistosoma mansoni | ||||
4. | ALA582072 | GNF-Pf-3264 | Toxicity | = | 0 | ALA2363023 | No effect | Schistosoma mansoni | ||||
5. | ALA582072 | GNF-Pf-3264 | Inhibition | = | 98.8 | % | ALA2094262 | % | Mycobacterium tuberculosis | |||
6. | ALA582072 | GNF-Pf-3264 | Inhibition | = | 11.8 | % | ALA2094261 | % | Mycobacterium tuberculosis | |||
7. | ALA582072 | GNF-Pf-3264 | LD50 | = | 5.37 | uM | ALA2094265 | uM | Homo sapiens | |||
8. | ALA582072 | GNF-Pf-3264 | MIC90 | = | 19.2 | uM | ALA2094264 | nM | Mycobacterium tuberculosis | |||
9. | ALA582072 | GNF-Pf-3264 | MIC90 | > | 100 | uM | ALA2094263 | nM | Mycobacterium tuberculosis | |||
10. | ALA582072 | GNF-Pf-3264 | IC50 | = | 2.735 | uM | ALA2028075 | 5.56 | nM | Trypanosoma brucei rhodesiense | ||
11. | ALA582072 | GNF-Pf-3264 | IC50 | = | 1.938 | uM | ALA2028074 | 5.71 | nM | Trypanosoma brucei brucei | ||
12. | ALA582072 | GNF-Pf-3264 | IC50 | = | 3.912 | uM | ALA2028073 | 5.41 | nM | Trypanosoma cruzi | ||
13. | ALA582072 | GNF-Pf-3264 | EC50 | = | 842 | nM | ALA2028071 | 6.08 | nM | Plasmodium falciparum | ||
14. | ALA582072 | GNF-Pf-3264 | Inhibition | = | 97 | % | ALA2028070 | % | Plasmodium falciparum | |||
15. | ALA582072 | GNF-Pf-3264 | IC50 | = | 8 | uM | ALA2028077 | 5.10 | nM | Homo sapiens | ||
16. | ALA582072 | GNF-Pf-3264 | IC50 | = | 4.057 | uM | ALA2028076 | 5.39 | nM | Leishmania infantum | ||
17. | ALA582072 | GNF-Pf-3264 | IC50 | = | 315.1 | nM | ALA3392923 | 6.50 | nM | Plasmodium falciparum | ||
18. | ALA582072 | GNF-Pf-3264 | IC50 | > | 1 | uM | ALA3301567 | nM | Plasmodium falciparum (isolate 3D7) | |||
19. | ALA582072 | GNF-Pf-3264 | IC50 | > | 1 | uM | ALA3301563 | nM | Plasmodium falciparum | |||
20. | ALA582072 | GNF-Pf-3264 | IC50 | > | 2.5 | uM | ALA3301569 | nM | Plasmodium falciparum (isolate 3D7) |