# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA582486 | GNF-Pf-3446 | Ratio | = | 8.9 | ALA4810694 | ||||||
2. | ALA582486 | GNF-Pf-3446 | INH | = | 88 | % | ALA4810691 | % | Homo sapiens | |||
3. | ALA582486 | GNF-Pf-3446 | INH | = | 48 | % | ALA4810690 | % | Homo sapiens | |||
4. | ALA582486 | GNF-Pf-3446 | INH | = | 12 | % | ALA4810689 | % | Homo sapiens | |||
5. | ALA582486 | GNF-Pf-3446 | INH | = | 8 | % | ALA4810688 | % | Homo sapiens | |||
6. | ALA582486 | GNF-Pf-3446 | CC50 | > | 100 | uM | ALA4810687 | nM | Homo sapiens | |||
7. | ALA582486 | GNF-Pf-3446 | EC50 | = | 6 | uM | ALA4810683 | 5.22 | nM | Cryptosporidium hominis | ||
8. | ALA582486 | GNF-Pf-3446 | EC50 | = | 2.1 | uM | ALA4810682 | 5.68 | nM | Cryptosporidium parvum | ||
9. | ALA582486 | GNF-Pf-3446 | t1/2 | > | 30 | min | ALA4810681 | hr | ||||
10. | ALA582486 | GNF-Pf-3446 | Kinetic_solubility | = | 200 | uM | ALA4810680 | nM | ||||
11. | ALA582486 | GNF-Pf-3446 | t1/2 | > | 30 | min | ALA4810679 | hr | ||||
12. | ALA582486 | GNF-Pf-3446 | IC50 | = | 1039 | nM | ALA3392923 | 5.98 | nM | Plasmodium falciparum | ||
13. | ALA582486 | GNF-Pf-3446 | IC50 | > | 1 | uM | ALA3301567 | nM | Plasmodium falciparum (isolate 3D7) | |||
14. | ALA582486 | GNF-Pf-3446 | IC50 | > | 1 | uM | ALA3301564 | nM | Plasmodium falciparum | |||
15. | ALA582486 | GNF-Pf-3446 | IC50 | > | 1 | uM | ALA3301563 | nM | Plasmodium falciparum | |||
16. | ALA582486 | GNF-Pf-3446 | IC50 | > | 2.5 | uM | ALA3301569 | nM | Plasmodium falciparum (isolate 3D7) | |||
17. | ALA582486 | GNF-Pf-3446 | IC50 | > | 1 | uM | ALA3301566 | nM | Plasmodium falciparum | |||
18. | ALA582486 | GNF-Pf-3446 | IC50 | > | 2.5 | uM | ALA3301568 | nM | Plasmodium falciparum (isolate 3D7) | |||
19. | ALA582486 | GNF-Pf-3446 | IC50 | > | 1 | uM | ALA3301565 | nM | Plasmodium falciparum | |||
20. | ALA582486 | GNF-Pf-3446 | Growth Inhibition | = | -0.542 | % | ALA3301556 | % | Plasmodium falciparum |