| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA594298 | 5, PARP-1 | IC50 | = | 24 | nM | ALA3428885 | 7.62 | nM | Homo sapiens | ||
| 2. | ALA594298 | 5, PARP-1 | EC50 | = | 3700 | nM | ALA3428886 | 5.43 | nM | Homo sapiens | ||
| 3. | ALA594298 | 5, PARP-1 | F | = | 41 | % | ALA3428887 | % | Rattus norvegicus | |||
| 4. | ALA594298 | 5, PARP-1 | CL | = | 30 | ml/min.kg | ALA3428888 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 5. | ALA594298 | 5, PARP-1 | beta t1/2 | = | 5.1 | hr | ALA3428889 | hr | Rattus norvegicus | |||
| 6. | ALA594298 | 5, PARP-1 | CL | 0 | ALA1116315 | Not Determined | Rattus norvegicus | |||||
| 7. | ALA594298 | 5, PARP-1 | IC50 | = | 24 | nM | ALA1115415 | 7.62 | nM | Homo sapiens | ||
| 8. | ALA594298 | 5, PARP-1 | EC50 | = | 3700 | nM | ALA1115416 | 5.43 | nM | Homo sapiens | ||
| 9. | ALA594298 | 5, PARP-1 | CL | = | 123 | uL/min/mg | ALA1115419 | mL.min-1.g-1 | Rattus norvegicus | |||
| 10. | ALA594298 | 5, PARP-1 | CL | = | 138 | uL/min/mg | ALA1115420 | mL.min-1.g-1 | ||||
| 11. | ALA594298 | 5, PARP-1 | CL | = | 30 | ml/min.kg | ALA1115421 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 12. | ALA594298 | 5, PARP-1 | F | = | 41 | % | ALA1115422 | % | Rattus norvegicus | |||
| 13. | ALA594298 | 5, PARP-1 | EC90 | = | 6200 | nM | ALA1115416 | nM | Homo sapiens | |||
| 14. | ALA594298 | 5, PARP-1 | Vd | = | 1.8 | L/Kg | ALA1115423 | L.kg-1 | Rattus norvegicus | |||
| 15. | ALA594298 | 5, PARP-1 | beta t1/2 | = | 5.1 | hr | ALA1115424 | hr | Rattus norvegicus | |||
| 16. | ALA594298 | 5, PARP-1 | IC50 | = | 25 | nM | ALA1065327 | 7.60 | nM | Homo sapiens |
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