| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA594025 | 5, PF-00277343 | Drug uptake | < | 1 | ng/ml | ALA1069199 | ng/ml | Macaca arctoides | |||
| 2. | ALA594025 | 5, PF-00277343 | Drug uptake | < | 1 | ng/ml | ALA1069198 | ng/ml | Macaca arctoides | |||
| 3. | ALA594025 | 5, PF-00277343 | Drug uptake | < | 2 | ng/ml | ALA1069197 | ng/ml | Macaca arctoides | |||
| 4. | ALA594025 | 5, PF-00277343 | Activity | 0 | ALA1069200 | Non-toxic | ||||||
| 5. | ALA594025 | 5, PF-00277343 | Activity | = | 0.1 | % | ALA1069196 | % | Macaca arctoides | |||
| 6. | ALA594025 | 5, PF-00277343 | Activity | 0 | ALA1069195 | Non-toxic | Mus musculus | |||||
| 7. | ALA594025 | 5, PF-00277343 | Activity | = | 9.88 | % | ALA1069194 | % | Homo sapiens | |||
| 8. | ALA594025 | 5, PF-00277343 | Activity | = | 0.58 | % | ALA1069193 | % | Homo sapiens | |||
| 9. | ALA594025 | 5, PF-00277343 | Activity | = | 6.17 | % | ALA1069192 | % | Homo sapiens | |||
| 10. | ALA594025 | 5, PF-00277343 | Activity | = | 0.14 | microg/cm2/h | ALA1069191 | microg/cm2/h | Homo sapiens | |||
| 11. | ALA594025 | 5, PF-00277343 | beta t1/2 | = | 2.73 | hr | ALA1069190 | hr | Rattus norvegicus | |||
| 12. | ALA594025 | 5, PF-00277343 | Vdss(app) | = | 4.88 | ml/min.kg | ALA1069189 | ml/min.kg | Rattus norvegicus | |||
| 13. | ALA594025 | 5, PF-00277343 | CL | = | 40 | ml/min.kg | ALA1069188 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 14. | ALA594025 | 5, PF-00277343 | t1/2 | = | 119 | min | ALA1069185 | hr | Homo sapiens | |||
| 15. | ALA594025 | 5, PF-00277343 | CL | = | 15 | ml/min.kg | ALA1069186 | mL.min-1.kg-1 | Homo sapiens | |||
| 16. | ALA594025 | 5, PF-00277343 | CL | = | 29 | ml/min.kg | ALA1069187 | mL.min-1.kg-1 | Homo sapiens | |||
| 17. | ALA594025 | 5, PF-00277343 | t1/2 | = | 39 | min | ALA1069184 | hr | Homo sapiens | |||
| 18. | ALA594025 | 5, PF-00277343 | CL | = | 149 | ml/min.kg | ALA1069183 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 19. | ALA594025 | 5, PF-00277343 | CL | = | 51 | ml/min.kg | ALA1069182 | mL.min-1.kg-1 | Rattus norvegicus | |||
| 20. | ALA594025 | 5, PF-00277343 | t1/2 | = | 45 | min | ALA1069181 | hr | Rattus norvegicus |
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