Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA1080575	10e	Activity		0		ALA1111471		Not Active		Rattus norvegicus
2.	ALA1080575	10e	Activity		0		ALA1111469		Dose-dependent effect		Rattus norvegicus
3.	ALA1080575	10e	Ki	=	669	nM	ALA1111450	6.17		nM	Homo sapiens
4.	ALA1080575	10e	Ki	=	624	nM	ALA1111449	6.21		nM	Homo sapiens
5.	ALA1080575	10e	solubility	=	550	ug ml-1	ALA1111459			ug.mL-1
6.	ALA1080575	10e	Efficacy	=	-34	%	ALA1111452			%	Homo sapiens
7.	ALA1080575	10e	Ratio	=	0.09		ALA1111468				Rattus norvegicus
8.	ALA1080575	10e	t1/2	=	0.8	hr	ALA1111464			hr	Rattus norvegicus
9.	ALA1080575	10e	Vdss	=	1.3	L/Kg	ALA1111466			L.kg-1	Rattus norvegicus
10.	ALA1080575	10e	logD	=	1.5		ALA1111460
11.	ALA1080575	10e	permeability	=	1.5	10'-6 cm/s	ALA1111461			10'-6 cm/s
12.	ALA1080575	10e	CL	=	3	ml/min/mg	ALA1111463			mL.min-1.g-1	Homo sapiens
13.	ALA1080575	10e	Ki	=	7	nM	ALA1111448	8.15		nM	Homo sapiens
14.	ALA1080575	10e	CL	=	16	ml/min/mg	ALA1111462			mL.min-1.g-1	Rattus norvegicus
15.	ALA1080575	10e	CL	=	30	ml/min.kg	ALA1111465			mL.min-1.kg-1	Rattus norvegicus
16.	ALA1080575	10e	F	=	32	%	ALA1111467			%	Rattus norvegicus
17.	ALA1080575	10e	Ki	=	515	nM	ALA1111451	6.29		nM	Homo sapiens