Activities

#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	Activity		0		ALA1109744		Dose-dependent effect		Rattus norvegicus
2.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	Ratio Ki	=	10000		ALA1115174
3.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	Activity		0		ALA1109743		Not Active		Rattus norvegicus
4.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	Activity		0		ALA1109742		Not Active
5.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	Activity		0		ALA1109741		Not Active		Rattus norvegicus
6.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	t1/2	=	440	min	ALA1109753			hr	Homo sapiens
7.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	t1/2	=	100	min	ALA1109752			hr	Homo sapiens
8.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	F	=	5.5	%	ALA1109751			%	Canis lupus familiaris
9.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	F	=	5.5	%	ALA1109750			%	Rattus norvegicus
10.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	Ratio	=	0.4		ALA1109749
11.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	Ratio	=	10		ALA1109748
12.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	Ratio	=	0.7		ALA1109747
13.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	Activity	=	0.036	%	ALA1109746			%	Rattus norvegicus
14.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	Activity		0		ALA1109745		Dose-dependent effect		Rattus norvegicus
15.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	Activity	=	76	%	ALA1109740			%	Homo sapiens
16.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	EC50	=	440	nM	ALA1109739	6.36		nM	Homo sapiens
17.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	EC50	>	10000	nM	ALA1109737			nM	Homo sapiens
18.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	Ki	=	12.8	nM	ALA1109736	7.89		nM	Homo sapiens
19.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	Activity	=	95	%	ALA1109735			%	Homo sapiens
20.	(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide	8	EC50	=	2.3	nM	ALA1115175	8.64		nM	Homo sapiens

1.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

Activity

0

ALA1109744

Dose-dependent effect

Rattus norvegicus

2.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

Ratio Ki

=

10000

ALA1115174

3.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

Activity

0

ALA1109743

Not Active

Rattus norvegicus

4.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

Activity

0

ALA1109742

Not Active

5.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

Activity

0

ALA1109741

Not Active

Rattus norvegicus

6.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

t1/2

=

440

min

ALA1109753

hr

Homo sapiens

7.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

t1/2

=

100

min

ALA1109752

hr

Homo sapiens

8.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

F

=

5.5

%

ALA1109751

%

Canis lupus familiaris

9.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

F

=

5.5

%

ALA1109750

%

Rattus norvegicus

10.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

Ratio

=

0.4

ALA1109749

11.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

Ratio

=

10

ALA1109748

12.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

Ratio

=

0.7

ALA1109747

13.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

Activity

=

0.036

%

ALA1109746

%

Rattus norvegicus

14.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

Activity

0

ALA1109745

Dose-dependent effect

Rattus norvegicus

15.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

Activity

=

76

%

ALA1109740

%

Homo sapiens

16.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

EC50

=

440

nM

ALA1109739

6.36

nM

Homo sapiens

17.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

EC50

>

10000

nM

ALA1109737

nM

Homo sapiens

18.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

Ki

=

12.8

nM

ALA1109736

7.89

nM

Homo sapiens

19.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

Activity

=

95

%

ALA1109735

%

Homo sapiens

20.

(S)-N-(4-((4,4-Dimethylcyclohexyl)oxy)-5-fluoro-2-methoxybenzyl)pyrrolidine-2-carboxamide

8

EC50

=

2.3

nM

ALA1115175

8.64

nM

Homo sapiens