# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1099326 | 15 | Activity | 0 | ALA1115522 | Toxic | Rattus norvegicus | |||||
2. | ALA1099326 | 15 | IC50 | > | 7.5 | uM | ALA1107485 | nM | Homo sapiens | |||
3. | ALA1099326 | 15 | IC50 | > | 7.5 | uM | ALA1107484 | nM | Homo sapiens | |||
4. | ALA1099326 | 15 | IC50 | > | 7.5 | uM | ALA1107483 | nM | Homo sapiens | |||
5. | ALA1099326 | 15 | IC50 | > | 7.5 | uM | ALA1107482 | nM | Homo sapiens | |||
6. | ALA1099326 | 15 | INH | 0 | ALA1107481 | Not Active | % | Homo sapiens | ||||
7. | ALA1099326 | 15 | IC50 | 0 | ALA1107480 | Not Determined | Homo sapiens | |||||
8. | ALA1099326 | 15 | IC50 | = | 143 | nM | ALA1107474 | 6.84 | nM | Homo sapiens | ||
9. | ALA1099326 | 15 | IC50 | = | 71 | nM | ALA1107473 | 7.15 | nM | Homo sapiens | ||
10. | ALA1099326 | 15 | solubility | = | 61 | ug ml-1 | ALA1107477 | ug.mL-1 | ||||
11. | ALA1099326 | 15 | CL | = | 28.14 | ml/min.kg | ALA1115516 | mL.min-1.kg-1 | Rattus norvegicus | |||
12. | ALA1099326 | 15 | solubility | = | 22.7 | ug ml-1 | ALA1107478 | ug.mL-1 | ||||
13. | ALA1099326 | 15 | CL | = | 14.9 | ml/min.kg | ALA1107479 | mL.min-1.kg-1 | Rattus norvegicus | |||
14. | ALA1099326 | 15 | F | = | 10 | % | ALA1108256 | % | Rattus norvegicus | |||
15. | ALA1099326 | 15 | Tmax | = | 5 | hr | ALA1108255 | hr | Rattus norvegicus | |||
16. | ALA1099326 | 15 | t1/2 | = | 4.52 | hr | ALA1115514 | hr | Rattus norvegicus | |||
17. | ALA1099326 | 15 | t1/2 | = | 4.52 | hr | ALA1107488 | hr | Rattus norvegicus | |||
18. | ALA1099326 | 15 | logD | = | 1.78 | ALA1107476 | ||||||
19. | ALA1099326 | 15 | Vdss | = | 1.55 | L/Kg | ALA1115515 | L.kg-1 | Rattus norvegicus | |||
20. | ALA1099326 | 15 | IC50 | = | 0.9 | uM | ALA1107487 | 6.05 | nM | Homo sapiens |