Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	Temanogrel	10k	IC50	=	23.1	nM	ALA1119619	7.64		nM
2.	Temanogrel	10k	INH	=	58	%	ALA1119769			%	Canis lupus familiaris
3.	Temanogrel	10k	INH	=	58	%	ALA1119768			%	Canis lupus familiaris
4.	Temanogrel	10k	INH		0		ALA1119767		Active	%	Canis lupus familiaris
5.	Temanogrel	10k	INH	=	57	%	ALA1119765			%	Canis lupus familiaris
6.	Temanogrel	10k	INH	=	58	%	ALA1119766			%	Canis lupus familiaris
7.	Temanogrel	10k	INH		0		ALA1119763		Active	%	Canis lupus familiaris
8.	Temanogrel	10k	BPR	=	0.05		ALA1119618
9.	Temanogrel	10k	Ratio Ki	>	2000		ALA1119617
10.	Temanogrel	10k	Ki	>	10000	nM	ALA1119616			nM	Homo sapiens
11.	Temanogrel	10k	F	=	16	%	ALA1119615			%	Macaca mulatta
12.	Temanogrel	10k	Vdss	=	0.6	L/Kg	ALA1119614			L.kg-1	Macaca mulatta
13.	Temanogrel	10k	CL	=	0.9	L/hr/kg	ALA1119613			mL.min-1.kg-1	Macaca mulatta
14.	Temanogrel	10k	t1/2	=	2.1	hr	ALA1119612			hr	Macaca mulatta
15.	Temanogrel	10k	AUC	=	1922	hr.ng/ml	ALA1119611			ng.hr.mL-1	Macaca mulatta
16.	Temanogrel	10k	Cmax	=	1462	ng/ml	ALA1119610		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Macaca mulatta
17.	Temanogrel	10k	F	=	45	%	ALA1119609			%	Canis lupus familiaris
18.	Temanogrel	10k	Vdss	=	1.3	L/Kg	ALA1119608			L.kg-1	Canis lupus familiaris
19.	Temanogrel	10k	CL	=	1.2	L/hr/kg	ALA1119607			mL.min-1.kg-1	Canis lupus familiaris
20.	Temanogrel	10k	t1/2	=	0.9	hr	ALA1119606			hr	Canis lupus familiaris