# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1170455 | Heptylalphaman | Activity | 0 | ALA2399354 | Dose-dependent effect | Escherichia coli K-12 | |||||
2. | ALA1170455 | Heptylalphaman | Kd | = | 5 | nM | ALA2399353 | 8.30 | nM | Escherichia coli K-12 | ||
3. | ALA1170455 | Heptylalphaman | Kd | = | 7 | nM | ALA2399352 | 8.15 | nM | Escherichia coli K-12 | ||
4. | ALA1170455 | Heptylalphaman | INH | 0 | ALA2399350 | Dose-dependent effect | % | Escherichia coli | ||||
5. | ALA1170455 | Heptylalphaman | Activity | = | 52.4 | % | ALA2399348 | % | Escherichia coli | |||
6. | ALA1170455 | Heptylalphaman | Activity | 0 | ALA2399355 | Not Active | Escherichia coli | |||||
7. | ALA1170455 | Heptylalphaman | log Pe | = | -4.89 | ALA3418232 | ||||||
8. | ALA1170455 | Heptylalphaman | t1/2 | = | 13 | min | ALA3419540 | hr | Rattus norvegicus | |||
9. | ALA1170455 | Heptylalphaman | PPB | = | 81 | % | ALA3419539 | % | ||||
10. | ALA1170455 | Heptylalphaman | Papp | = | 9.4 | 10'-6 cm/s | ALA3419538 | 10'-6 cm/s | ||||
11. | ALA1170455 | Heptylalphaman | Papp | = | 7 | 10'-6 cm/s | ALA3419537 | 10'-6 cm/s | ||||
12. | ALA1170455 | Heptylalphaman | Kinetic_solubility | > | 3000 | ug ml-1 | ALA3419535 | ug.mL-1 | ||||
13. | ALA1170455 | Heptylalphaman | logD | = | 1.65 | ALA3419534 | ||||||
14. | ALA1170455 | Heptylalphaman | Kd | = | 28.9 | nM | ALA3419530 | 7.54 | nM | |||
15. | ALA1170455 | Heptylalphaman | Kd | = | 28.3 | nM | ALA3419529 | 7.55 | nM | |||
16. | ALA1170455 | Heptylalphaman | Kd | = | 35.6 | nM | ALA4820003 | 7.45 | nM | |||
17. | ALA1170455 | Heptylalphaman | Kd | = | 36.8 | nM | ALA4820002 | 7.43 | nM | Escherichia coli K-12 | ||
18. | ALA1170455 | Heptylalphaman | Selectivity ratio | = | 100 | ALA4015743 | ||||||
19. | ALA1170455 | Heptylalphaman | Kd | = | 3.2 | 10'-6M | ALA4015742 | 5.50 | nM | |||
20. | ALA1170455 | Heptylalphaman | log Pe | 0 | ALA4015741 | Not Determined |