# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1172425 | 50 | Activity | = | 77 | % | ALA1176089 | % | Mus musculus | |||
2. | ALA1172425 | 50 | Activity | = | 56 | % | ALA1176090 | % | Mus musculus | |||
3. | ALA1172425 | 50 | Activity | = | 27 | % | ALA1176091 | % | Mus musculus | |||
4. | ALA1172425 | 50 | F | = | 35.8 | % | ALA1176092 | % | Mus musculus | |||
5. | ALA1172425 | 50 | AUC | = | 3.17 | microg.hr/mL | ALA1176109 | ng.hr.mL-1 | Mus musculus | |||
6. | ALA1172425 | 50 | AUC | = | 8.86 | microg.hr/mL | ALA1176093 | ng.hr.mL-1 | Mus musculus | |||
7. | ALA1172425 | 50 | t1/2 | = | 0.76 | hr | ALA1176094 | hr | Mus musculus | |||
8. | ALA1172425 | 50 | Vd | = | 0.12 | L/Kg | ALA1176095 | L.kg-1 | Mus musculus | |||
9. | ALA1172425 | 50 | CL | = | 1.88 | ml/min.kg | ALA1176096 | mL.min-1.kg-1 | Mus musculus | |||
10. | ALA1172425 | 50 | Cp | = | 6.89 | ug ml-1 | ALA1176385 | ug ml-1 | Mus musculus | |||
11. | ALA1172425 | 50 | Activity | 0 | ALA1176088 | Not Active | Mus musculus | |||||
12. | ALA1172425 | 50 | Activity | 0 | ALA1176097 | Active | Mus musculus | |||||
13. | ALA1172425 | 50 | IC50 | = | 0.539 | uM | ALA1176099 | 6.27 | nM | Rattus norvegicus | ||
14. | ALA1172425 | 50 | IC50 | = | 1.77 | uM | ALA1176110 | 5.75 | nM | Mus musculus | ||
15. | ALA1172425 | 50 | IC50 | = | 1.79 | uM | ALA1176100 | 5.75 | nM | Homo sapiens | ||
16. | ALA1172425 | 50 | Efficacy | = | 45 | % | ALA1176102 | % | Rattus norvegicus | |||
17. | ALA1172425 | 50 | Efficacy | = | 59 | % | ALA1176103 | % | Mus musculus | |||
18. | ALA1172425 | 50 | EC50 | = | 0.158 | uM | ALA1176104 | 6.80 | nM | Rattus norvegicus | ||
19. | ALA1172425 | 50 | EC50 | = | 0.158 | uM | ALA1176273 | 6.80 | nM | Mus musculus | ||
20. | ALA1172425 | 50 | Activity | 0 | ALA1176098 | Not Active | Mus musculus |