# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1172929 | (2R,3R)-4a | LogD7.4 | 1.69 | ALA3301363 | |||||||
2. | ALA1172929 | (2R,3R)-4a | AD50 | 0 | ALA1768552 | Not Determined | Mus musculus | |||||
3. | ALA1172929 | (2R,3R)-4a | AD50 | > | 20 | mg kg-1 | ALA1768551 | mg kg-1 | Mus musculus | |||
4. | ALA1172929 | (2R,3R)-4a | AD50 | > | 20 | mg kg-1 | ALA1768550 | mg kg-1 | Mus musculus | |||
5. | ALA1172929 | (2R,3R)-4a | AD50 | = | 3.9 | mg kg-1 | ALA1768549 | mg kg-1 | Mus musculus | |||
6. | ALA1172929 | (2R,3R)-4a | AD50 | = | 1.26 | mg kg-1 | ALA1768457 | mg kg-1 | Mus musculus | |||
7. | ALA1172929 | (2R,3R)-4a | IC50 | = | 9.4 | uM | ALA1768456 | 5.03 | nM | Homo sapiens | ||
8. | ALA1172929 | (2R,3R)-4a | IC50 | = | 12 | uM | ALA1768455 | 4.92 | nM | Homo sapiens | ||
9. | ALA1172929 | (2R,3R)-4a | IC50 | = | 17 | uM | ALA1768263 | 4.77 | nM | Homo sapiens | ||
10. | ALA1172929 | (2R,3R)-4a | IC50 | = | 1.6 | uM | ALA1769983 | 5.80 | nM | Homo sapiens | ||
11. | ALA1172929 | (2R,3R)-4a | IC50 | > | 100 | nM | ALA1768262 | nM | Homo sapiens | |||
12. | ALA1172929 | (2R,3R)-4a | IC50 | = | 1200 | nM | ALA1769985 | 5.92 | nM | Homo sapiens | ||
13. | ALA1172929 | (2R,3R)-4a | IC50 | = | 1600 | nM | ALA1769984 | 5.80 | nM | Homo sapiens | ||
14. | ALA1172929 | (2R,3R)-4a | Activity | 0 | ALA1176859 | Non-toxic | Mus musculus | |||||
15. | ALA1172929 | (2R,3R)-4a | Activity | 0 | ALA1176858 | Non-toxic | Mus musculus | |||||
16. | ALA1172929 | (2R,3R)-4a | IC50 | > | 15 | mg kg-1 | ALA1176305 | mg kg-1 | Mus musculus | |||
17. | ALA1172929 | (2R,3R)-4a | IC50 | = | 630 | nM | ALA1176113 | 6.20 | nM | Homo sapiens | ||
18. | ALA1172929 | (2R,3R)-4a | IC50 | = | 241 | nM | ALA1176114 | 6.62 | nM | Homo sapiens | ||
19. | ALA1172929 | (2R,3R)-4a | IC50 | > | 100 | uM | ALA1176115 | nM | Homo sapiens | |||
20. | ALA1172929 | (2R,3R)-4a | IC50 | = | 11 | uM | ALA1176286 | 4.96 | nM | Homo sapiens |