| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA9861 | 1 | pKa_B1 | 3.1 | ALA3301362 | "B1 Functional Group: Pyridine; Ionisation Formula: A1B1 (Functional Group: the part of the molecule the pKa refers to; Ionisation formula: AxBy where 'A' refers to acidic centers within the molecule that are appreciably ionised at a pH <= 11 and 'x' equals 0, 1 or 2; and 'B' refers to basic centers within the molecule that are appreciably ionised at a pH >= 2 and 'y' equals 0, 1, 2 or 3)." | ||||||
| 2. | ALA9861 | 1 | pKa_A1 | 8.8 | ALA3301375 | "A1 Functional Group: 1H-benzimidazole, 2-(methylsulfinyl)-; Ionisation Formula: A1B1 (Functional Group: the part of the molecule the pKa refers to; Ionisation formula: AxBy where 'A' refers to acidic centers within the molecule that are appreciably ionised at a pH <= 11 and 'x' equals 0, 1 or 2; and 'B' refers to basic centers within the molecule that are appreciably ionised at a pH >= 2 and 'y' equals 0, 1, 2 or 3)." | ||||||
| 3. | ALA9861 | 1 | -Log IC50(M) | = | 3.51 | ALA1063294 | nM | Homo sapiens | ||||
| 4. | ALA9861 | 1 | ED50 | = | 2.5 | mg kg-1 | ALA779695 | mg.kg-1 | Rattus norvegicus | |||
| 5. | ALA9861 | 1 | ED50 | = | 4 | mg kg-1 | ALA690658 | mg.kg-1 | Rattus norvegicus | |||
| 6. | ALA9861 | 1 | Inhibition | = | 27 | % | ALA687662 | % | Sus scrofa | |||
| 7. | ALA9861 | 1 | ID50 | = | 0 | M | ALA768177 | M | Oryctolagus cuniculus | |||
| 8. | ALA9861 | 1 | Inhibition | = | 68 | % | ALA667789 | % | Canis lupus familiaris | |||
| 9. | ALA9861 | 1 | IC50 | = | 130 | uM | ALA689040 | nM | Homo sapiens |
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