# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1221916 | 30 | Kd | = | 4.3 | nM | ALA1227179 | 8.37 | nM | Homo sapiens | ||
2. | ALA1221916 | 30 | Ki | > | 25 | uM | ALA1227182 | nM | Homo sapiens | |||
3. | ALA1221916 | 30 | pKa | = | 2.75 | ALA1227366 | ||||||
4. | ALA1221916 | 30 | Phospholipidosis | 0 | ALA1227365 | Not Active | ||||||
5. | ALA1221916 | 30 | Activity | 0 | ALA1227364 | Non-toxic | ||||||
6. | ALA1221916 | 30 | Ki | > | 33 | uM | ALA1227363 | nM | Homo sapiens | |||
7. | ALA1221916 | 30 | Ki | > | 33 | uM | ALA1227362 | nM | ||||
8. | ALA1221916 | 30 | Ki | > | 33 | uM | ALA1227361 | nM | Homo sapiens | |||
9. | ALA1221916 | 30 | AUC | = | 6700 | ng.hr/ml | ALA1227360 | ng.hr.mL-1 | Macaca fascicularis | |||
10. | ALA1221916 | 30 | Vdss | = | 0.44 | L/Kg | ALA1227359 | L.kg-1 | Macaca fascicularis | |||
11. | ALA1221916 | 30 | CL | = | 1.8 | ml/min.kg | ALA1227358 | mL.min-1.kg-1 | Macaca fascicularis | |||
12. | ALA1221916 | 30 | t1/2 | = | 5 | hr | ALA1227357 | hr | Macaca fascicularis | |||
13. | ALA1221916 | 30 | F | = | 64 | % | ALA1227356 | % | Macaca fascicularis | |||
14. | ALA1221916 | 30 | AUC | = | 2300 | ng.hr/ml | ALA1227355 | ng.hr.mL-1 | Rattus norvegicus | |||
15. | ALA1221916 | 30 | Vdss | = | 0.42 | L/Kg | ALA1227354 | L.kg-1 | Rattus norvegicus | |||
16. | ALA1221916 | 30 | CL | = | 7.3 | ml/min.kg | ALA1227353 | mL.min-1.kg-1 | Rattus norvegicus | |||
17. | ALA1221916 | 30 | t1/2 | = | 1.5 | hr | ALA1227352 | hr | Rattus norvegicus | |||
18. | ALA1221916 | 30 | F | = | 100 | % | ALA1227351 | % | Rattus norvegicus | |||
19. | ALA1221916 | 30 | IC50 | > | 10 | uM | ALA1227350 | nM | Homo sapiens | |||
20. | ALA1221916 | 30 | CL | = | 0.2 | ml/min.kg | ALA1227349 | mL.min-1.kg-1 | Homo sapiens |