Activities

#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	Activity	=	100	%	ALA3056290			%	Rattus norvegicus
2.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	Activity	=	73	%	ALA3057689			%	Rattus norvegicus
3.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	logD	=	-2.83		ALA3533246
4.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	logPapp	=	-4.7		ALA3533248
5.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	INH		0		ALA3382038		Not Active	%	Homo sapiens
6.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	INH		0		ALA3382037		Not Active	%	Homo sapiens
7.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	Activity		0		ALA3382034		Not Active		Homo sapiens
8.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	FC		0		ALA3382032		Not Active		Homo sapiens
9.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	Kd	=	290	nM	ALA3369572	6.54		nM
10.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	Activity	=	78.7	%	ALA3378743			%	Rattus norvegicus
11.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	Activity	=	64.1	%	ALA3378177			%	Rattus norvegicus
12.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	Activity		0		ALA4479664		Active
13.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	pIC50	<	4.7		ALA4651403		No. Measurements = 3	nM	Severe acute respiratory syndrome coronavirus 2
14.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	IC50	>	0	M	ALA4651403		No. Measurements = 3	nM	Severe acute respiratory syndrome coronavirus 2
15.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	DILI_Concern		0		ALA4029350		No-Dili-Concern		Homo sapiens
16.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	DILI_severity_class	=	0		ALA4029349				Homo sapiens
17.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	INH	<	50	%	ALA4419299			%	Homo sapiens
18.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	I50		0		ALA4419300		Not Active		Homo sapiens
19.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	Hit score	=	0.072		ALA4303810				Severe acute respiratory syndrome coronavirus 2
20.	rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol	D-Glucose	Activity	=	97	%	ALA4265550			%

1.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

Activity

=

100

%

ALA3056290

%

Rattus norvegicus

2.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

Activity

=

73

%

ALA3057689

%

Rattus norvegicus

3.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

logD

=

-2.83

ALA3533246

4.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

logPapp

=

-4.7

ALA3533248

5.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

INH

0

ALA3382038

Not Active

%

Homo sapiens

6.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

INH

0

ALA3382037

Not Active

%

Homo sapiens

7.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

Activity

0

ALA3382034

Not Active

Homo sapiens

8.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

FC

0

ALA3382032

Not Active

Homo sapiens

9.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

Kd

=

290

nM

ALA3369572

6.54

nM

10.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

Activity

=

78.7

%

ALA3378743

%

Rattus norvegicus

11.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

Activity

=

64.1

%

ALA3378177

%

Rattus norvegicus

12.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

Activity

0

ALA4479664

Active

13.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

pIC50

<

4.7

ALA4651403

No. Measurements = 3

nM

Severe acute respiratory syndrome coronavirus 2

14.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

IC50

>

0

M

ALA4651403

No. Measurements = 3

nM

Severe acute respiratory syndrome coronavirus 2

15.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

DILI_Concern

0

ALA4029350

No-Dili-Concern

Homo sapiens

16.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

DILI_severity_class

=

0

ALA4029349

Homo sapiens

17.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

INH

<

50

%

ALA4419299

%

Homo sapiens

18.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

I50

0

ALA4419300

Not Active

Homo sapiens

19.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

Hit score

=

0.072

ALA4303810

Severe acute respiratory syndrome coronavirus 2

20.

rel-(3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

D-Glucose

Activity

=

97

%

ALA4265550

%