# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1232960 | HICA | t1/2 | = | 1.1 | hr | ALA5236861 | hr | ||||
2. | ALA1232960 | HICA | t1/2 | = | 1.6 | hr | ALA5236860 | hr | ||||
3. | ALA1232960 | HICA | Cmax | = | 158 | uM | ALA5236859 | nM | ||||
4. | ALA1232960 | HICA | Cmax | = | 153 | uM | ALA5236858 | nM | ||||
5. | ALA1232960 | HICA | Activity | = | 100 | % | ALA5236857 | % | Plasmodium falciparum | |||
6. | ALA1232960 | HICA | Activity | = | 30 | % | ALA5236856 | % | Plasmodium falciparum | |||
7. | ALA1232960 | HICA | EC90 | > | 200 | uM | ALA5236852 | uM | Plasmodium falciparum | |||
8. | ALA1232960 | HICA | EC50 | = | 74.4 | uM | ALA5236852 | 4.13 | nM | Plasmodium falciparum | ||
9. | ALA1232960 | HICA | Ki | = | 470 | nM | ALA5236851 | 6.33 | nM | |||
10. | ALA1232960 | HICA | IC50 | = | 54 | uM | ALA5236848 | 4.27 | nM | |||
11. | ALA1232960 | HICA | IC50 | = | 1.1 | uM | ALA5236847 | 5.96 | nM | Plasmodium falciparum | ||
12. | ALA1232960 | HICA | IC50 | = | 54 | uM | ALA1692976 | 4.27 | nM | Homo sapiens |