# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1236677 | VNI | Activity | = | 60 | % | ALA3631890 | % | Leishmania | |||
2. | ALA1236677 | VNI | IC50 | = | 0.9 | uM | ALA5246281 | 6.05 | nM | Trypanosoma cruzi | ||
3. | ALA1236677 | VNI | IC50 | = | 11 | uM | ALA5246277 | 4.96 | nM | Trypanosoma cruzi | ||
4. | ALA1236677 | VNI | IC50 | = | 0.25 | uM | ALA4125300 | 6.60 | nM | Aspergillus | ||
5. | ALA1236677 | VNI | IC50 | = | 0.25 | uM | ALA4125299 | 6.60 | nM | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | ||
6. | ALA1236677 | VNI | MIC100 | = | 0.08 | ug ml-1 | ALA4125298 | ug ml-1 | Aspergillus fumigatus | |||
7. | ALA1236677 | VNI | MIC100 | = | 0.08 | ug ml-1 | ALA4125297 | ug ml-1 | Aspergillus fumigatus | |||
8. | ALA1236677 | VNI | MIC100 | = | 0.48 | ug ml-1 | ALA4125296 | ug ml-1 | Aspergillus fumigatus | |||
9. | ALA1236677 | VNI | t1/2 | = | 62 | min | ALA4125295 | hr | ||||
10. | ALA1236677 | VNI | CLH | = | 44 | ml/min.kg | ALA4125294 | mL.min-1.kg-1 | ||||
11. | ALA1236677 | VNI | CLH | = | 87 | ml/min.kg | ALA4125293 | mL.min-1.kg-1 | ||||
12. | ALA1236677 | VNI | t1/2 | = | 106 | min | ALA4125292 | hr | ||||
13. | ALA1236677 | VNI | CLH | = | 19.2 | ml/min.kg | ALA4125291 | mL.min-1.kg-1 | ||||
14. | ALA1236677 | VNI | CLH | = | 26.4 | ml/min.kg | ALA4125290 | mL.min-1.kg-1 | ||||
15. | ALA1236677 | VNI | t1/2 | = | 150 | min | ALA4125289 | hr | ||||
16. | ALA1236677 | VNI | CLH | = | 5.95 | ml/min.kg | ALA4125288 | mL.min-1.kg-1 | ||||
17. | ALA1236677 | VNI | CLH | = | 8.31 | ml/min.kg | ALA4125287 | mL.min-1.kg-1 | ||||
18. | ALA1236677 | VNI | Kd(app) | = | 203 | nM | ALA4125284 | 6.69 | nM | Aspergillus | ||
19. | ALA1236677 | VNI | Kd(app) | = | 290 | nM | ALA4125283 | 6.54 | nM | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | ||
20. | ALA1236677 | VNI | logP | = | 4.57 | ALA4125282 |