# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1258702 | 2 | Activity | 0 | ALA4271588 | Active | Staphylococcus aureus | |||||
2. | ALA1258702 | 2 | Activity | 0 | ALA4271587 | Active | ||||||
3. | ALA1258702 | 2 | INH | = | 98.1 | % | ALA4271581 | % | ||||
4. | ALA1258702 | 2 | IC50 | = | 160 | uM | ALA4271580 | nM | ||||
5. | ALA1258702 | 2 | IC50 | = | 26.2 | uM | ALA4271579 | 4.58 | nM | |||
6. | ALA1258702 | 2 | IC50 | = | 10 | uM | ALA1261150 | 5.00 | nM | Homo sapiens | ||
7. | ALA1258702 | 2 | IC50 | = | 0.5 | uM | ALA1261149 | 6.30 | nM | |||
8. | ALA1258702 | 2 | t1/2 | = | 2.7 | hr | ALA1261226 | hr | Mus musculus | |||
9. | ALA1258702 | 2 | Tmax | = | 4 | hr | ALA1261225 | hr | Mus musculus | |||
10. | ALA1258702 | 2 | Cmax | = | 26400 | ng/ml | ALA1261224 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
11. | ALA1258702 | 2 | AUC | = | 263289 | ng.hr/ml | ALA1261223 | ng.hr.mL-1 | Mus musculus | |||
12. | ALA1258702 | 2 | t1/2 | = | 2.9 | hr | ALA1261222 | hr | Mus musculus | |||
13. | ALA1258702 | 2 | Vdss | = | 3.5 | L/Kg | ALA1261221 | L.kg-1 | Mus musculus | |||
14. | ALA1258702 | 2 | CL | = | 11.2 | ml/min.kg | ALA1261220 | mL.min-1.kg-1 | Mus musculus | |||
15. | ALA1258702 | 2 | AUC | = | 14809 | ng.hr/ml | ALA1261219 | ng.hr.mL-1 | Mus musculus | |||
16. | ALA1258702 | 2 | IC50 | = | 6 | uM | ALA1261148 | 5.22 | nM | Homo sapiens | ||
17. | ALA1258702 | 2 | IC50 | = | 0.07 | uM | ALA1261151 | 7.16 | nM | Homo sapiens |