| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA1276315 | QPT-1, PNU-286607 | MIC | = | 1 | ug ml-1 | ALA1281316 | ug.mL-1 | Streptococcus pneumoniae | |||
| 2. | ALA1276315 | QPT-1, PNU-286607 | MIC | = | 2 | ug ml-1 | ALA1281315 | ug.mL-1 | Streptococcus pneumoniae | |||
| 3. | ALA1276315 | QPT-1, PNU-286607 | MIC | = | 0.5 | ug ml-1 | ALA1281314 | ug.mL-1 | Staphylococcus aureus | |||
| 4. | ALA1276315 | QPT-1, PNU-286607 | MIC | = | 1 | ug ml-1 | ALA1281313 | ug.mL-1 | Staphylococcus aureus | |||
| 5. | ALA1276315 | QPT-1, PNU-286607 | MIC | = | 0.5 | ug ml-1 | ALA1281312 | ug.mL-1 | Staphylococcus aureus | |||
| 6. | ALA1276315 | QPT-1, PNU-286607 | MIC | = | 1 | ug ml-1 | ALA1281304 | ug.mL-1 | Staphylococcus aureus | |||
| 7. | ALA1276315 | QPT-1, PNU-286607 | MIC | = | 4 | ug ml-1 | ALA1281303 | ug.mL-1 | Staphylococcus aureus | |||
| 8. | ALA1276315 | QPT-1, PNU-286607 | MIC | = | 16 | ug ml-1 | ALA1281302 | ug.mL-1 | Staphylococcus aureus | |||
| 9. | ALA1276315 | QPT-1, PNU-286607 | Activity | 0 | ALA1281446 | Non-toxic | Mus musculus | |||||
| 10. | ALA1276315 | QPT-1, PNU-286607 | ED50 | = | 12.5 | mg kg-1 | ALA1281445 | mg.kg-1 | Staphylococcus aureus | |||
| 11. | ALA1276315 | QPT-1, PNU-286607 | ED50 | = | 19.5 | mg kg-1 | ALA1281444 | mg.kg-1 | Staphylococcus aureus | |||
| 12. | ALA1276315 | QPT-1, PNU-286607 | INH | 0 | ALA1281457 | Non-toxic | % | Mus musculus | ||||
| 13. | ALA1276315 | QPT-1, PNU-286607 | IC50 | = | 200 | uM | ALA1281319 | nM | ||||
| 14. | ALA1276315 | QPT-1, PNU-286607 | IC50 | = | 30 | uM | ALA1281318 | 4.52 | nM | |||
| 15. | ALA1276315 | QPT-1, PNU-286607 | F | = | 94.7 | % | ALA1281456 | % | Mus musculus | |||
| 16. | ALA1276315 | QPT-1, PNU-286607 | Tmax | = | 1 | hr | ALA1281455 | hr | Mus musculus | |||
| 17. | ALA1276315 | QPT-1, PNU-286607 | AUC | = | 27.6 | microg.hr/mL | ALA1281454 | ng.hr.mL-1 | Mus musculus | |||
| 18. | ALA1276315 | QPT-1, PNU-286607 | Cmax | = | 15.7 | ug ml-1 | ALA1281453 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Mus musculus | ||
| 19. | ALA1276315 | QPT-1, PNU-286607 | t1/2 | = | 0.927 | hr | ALA1281452 | hr | Mus musculus | |||
| 20. | ALA1276315 | QPT-1, PNU-286607 | CL | = | 0.697 | L/kg/hr | ALA1281451 | mL.min-1.kg-1 | Mus musculus |
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