# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1277935 | 48, stereoisomer2 | pKi | = | 7.6 | ALA1287093 | 7.60 | nM | Homo sapiens | |||
2. | ALA1277935 | 48, stereoisomer2 | pKi | = | 7.7 | ALA1287093 | 7.70 | nM | Homo sapiens | |||
3. | ALA1277935 | 48, stereoisomer2 | pKi | = | 6.9 | ALA1287094 | 6.90 | nM | Homo sapiens | |||
4. | ALA1277935 | 48, stereoisomer2 | pKi | < | 5.7 | ALA1287094 | nM | Homo sapiens | ||||
5. | ALA1277935 | 48, stereoisomer2 | pKi | < | 5.7 | ALA1287095 | nM | Homo sapiens | ||||
6. | ALA1277935 | 48, stereoisomer2 | pKi | < | 5.7 | ALA1287095 | nM | Homo sapiens | ||||
7. | ALA1277935 | 48, stereoisomer2 | pKi | = | 6.8 | ALA1287096 | 6.80 | nM | Homo sapiens | |||
8. | ALA1277935 | 48, stereoisomer2 | pKi | < | 5.7 | ALA1287096 | nM | Homo sapiens | ||||
9. | ALA1277935 | 48, stereoisomer2 | pKi | = | 8.06 | ALA1287099 | 8.06 | nM | Rattus norvegicus | |||
10. | ALA1277935 | 48, stereoisomer2 | pKi | = | 6.93 | ALA1287100 | 6.93 | nM | Rattus norvegicus | |||
11. | ALA1277935 | 48, stereoisomer2 | pIC50 | < | 4.4 | ALA1287098 | nM | Homo sapiens | ||||
12. | ALA1277935 | 48, stereoisomer2 | CL | < | 0.5 | ml/min/g | ALA1287101 | mL.min-1.g-1 | Rattus norvegicus | |||
13. | ALA1277935 | 48, stereoisomer2 | CL | < | 0.5 | ml/min/g | ALA1287102 | mL.min-1.g-1 | Homo sapiens | |||
14. | ALA1277935 | 48, stereoisomer2 | IC50 | > | 10 | uM | ALA1287103 | nM | Homo sapiens | |||
15. | ALA1277935 | 48, stereoisomer2 | IC50 | > | 10 | uM | ALA1287104 | nM | Homo sapiens | |||
16. | ALA1277935 | 48, stereoisomer2 | IC50 | > | 10 | uM | ALA1287105 | nM | Homo sapiens | |||
17. | ALA1277935 | 48, stereoisomer2 | IC50 | > | 10 | uM | ALA1287106 | nM | Homo sapiens | |||
18. | ALA1277935 | 48, stereoisomer2 | IC50 | > | 10 | uM | ALA1287107 | nM | Homo sapiens | |||
19. | ALA1277935 | 48, stereoisomer2 | Fu | = | 3 | % | ALA1287108 | Rattus norvegicus | ||||
20. | ALA1277935 | 48, stereoisomer2 | Fu | = | 2.4 | % | ALA1287109 | Rattus norvegicus |