Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA45816	Mibefradil	AC50	=	1.58	uM	ALA5291731	5.80	Summarised AC50 (mean value for measurements with a relation sign "="; largest value for measurements with relation sign ">")	nM	Homo sapiens
2.	ALA45816	Mibefradil	AC50	=	21.861	uM	ALA5291887	4.66	Summarised AC50 (mean value for measurements with a relation sign "="; largest value for measurements with relation sign ">")	nM	Homo sapiens
3.	ALA45816	Mibefradil	IC50	=	1.1	uM	ALA3638107	5.96	Original reference for datapoint is pubmed_id: 22293482	nM	Rattus norvegicus
4.	ALA45816	Mibefradil	Stability	=	64	%	ALA3385970			%	Homo sapiens
5.	ALA45816	Mibefradil	Stability	=	43	%	ALA3363901			%	Homo sapiens
6.	ALA45816	Mibefradil	IC50	=	500	nM	ALA4181851	6.30		nM	Homo sapiens
7.	ALA45816	Mibefradil	IC50	=	500	nM	ALA4181850	6.30		nM	Rattus norvegicus
8.	ALA45816	Mibefradil	IC50	=	500	nM	ALA4181849	6.30		nM	Rattus norvegicus
9.	ALA45816	Mibefradil	IC50	=	500	nM	ALA4181848	6.30		nM	Homo sapiens
10.	ALA45816	Mibefradil	IC50	=	1000	nM	ALA4181847	6.00		nM	Rattus norvegicus
11.	ALA45816	Mibefradil	IC50	=	1000	nM	ALA4181846	6.00		nM
12.	ALA45816	Mibefradil	IC50	=	580	nM	ALA4181845	6.24		nM	Homo sapiens
13.	ALA45816	Mibefradil	IC50	=	250	nM	ALA4181844	6.60		nM	Homo sapiens
14.	ALA45816	Mibefradil	IC50	=	130	nM	ALA4181843	6.89		nM	Homo sapiens
15.	ALA45816	Mibefradil	IC50	=	130	nM	ALA4181842	6.89		nM	Homo sapiens
16.	ALA45816	Mibefradil	IC50	=	64	nM	ALA4181841	7.19		nM	Homo sapiens
17.	ALA45816	Mibefradil	IC50	=	4.32	uM	ALA4049313	5.37		nM
18.	ALA45816	Mibefradil	Potency		31.623	uM	ALA3562077		inconclusive	nM
19.	ALA45816	Mibefradil	logD	=	3.66		ALA3533246
20.	ALA45816	Mibefradil	logPapp	=	-4.87		ALA3533248