# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA45816 | Mibefradil | Potency | 29.093 | uM | ALA2354282 | inconclusive | nM | Homo sapiens | |||
2. | ALA45816 | Mibefradil | Potency | 19.953 | uM | ALA2114784 | active | nM | Homo sapiens | |||
3. | ALA45816 | Mibefradil | IC50 | = | 0.873 | nM | ALA2090728 | 9.06 | nM | Plasmodium yoelii yoelii | ||
4. | ALA45816 | Mibefradil | IC50 | = | 7.4 | uM | ALA2076206 | 5.13 | inhibitor [IC50=7.4uM] | nM | Mus musculus | |
5. | ALA45816 | Mibefradil | IC50 | = | 10 | uM | ALA2076215 | 5.00 | inhibitor [IC50=10uM] | nM | Mus musculus | |
6. | ALA45816 | Mibefradil | IC50 | = | 1.8 | uM | ALA2076209 | 5.75 | inhibitor [IC50=1.8uM] | nM | Homo sapiens | |
7. | ALA45816 | Mibefradil | IC50 | = | 1.6 | uM | ALA2075167 | 5.80 | inhibitor [IC50=1.6uM] | nM | Homo sapiens | |
8. | ALA45816 | Mibefradil | IC50 | = | 1.2 | uM | ALA2075362 | 5.92 | inhibitor [IC50=1.2uM] | nM | Homo sapiens | |
9. | ALA45816 | Mibefradil | Activity | = | 60 | % | ALA2076207 | inhibitor [60 % of control] | % | Homo sapiens | ||
10. | ALA45816 | Mibefradil | Activity | 0 | ALA2075823 | inhibitor [+] | Homo sapiens | |||||
11. | ALA45816 | Mibefradil | INH | = | 81 | % | ALA2339144 | % | Homo sapiens | |||
12. | ALA45816 | Mibefradil | IC50 | = | 0.83 | uM | ALA2339145 | 6.08 | nM | Homo sapiens | ||
13. | ALA45816 | Mibefradil | IC50 | = | 1.4 | uM | ALA2339143 | 5.85 | nM | Homo sapiens | ||
14. | ALA45816 | Mibefradil | IC50 | = | 1 | uM | ALA2344013 | 6.00 | nM | Homo sapiens | ||
15. | ALA45816 | Mibefradil | IC50 | = | 3.3 | uM | ALA2344015 | 5.48 | nM | Homo sapiens | ||
16. | ALA45816 | Mibefradil | CLH | = | 56.5 | microL/min/mg | ALA2344012 | mL.min-1.g-1 | Homo sapiens | |||
17. | ALA45816 | Mibefradil | IC50 | = | 0.063 | uM | ALA2344011 | 7.20 | nM | Homo sapiens | ||
18. | ALA45816 | Mibefradil | Drug metabolism | 0 | ALA2344010 | Active | Homo sapiens | |||||
19. | ALA45816 | Mibefradil | Ratio IC50 | = | 1.69 | ALA2339142 | ||||||
20. | ALA45816 | Mibefradil | Ratio | = | 2143 | ml/min/umol | ALA3530943 | ml/min/umol | Homo sapiens |