# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA1354431 | SID85147395 | LC50 | > | 50 | uM | ALA3375698 | nM | ||||
2. | ALA1354431 | SID85147395 | Stability | = | 100 | % | ALA3375705 | % | Mus musculus | |||
3. | ALA1354431 | SID85147395 | Stability | = | 100 | % | ALA3375703 | % | Homo sapiens | |||
4. | ALA1354431 | SID85147395 | Stability | = | 71.2 | % | ALA3375702 | % | Mus musculus | |||
5. | ALA1354431 | SID85147395 | Stability | = | 100 | % | ALA3375701 | % | Mus musculus | |||
6. | ALA1354431 | SID85147395 | Stability | = | 55.5 | % | ALA3375700 | % | Homo sapiens | |||
7. | ALA1354431 | SID85147395 | Stability | = | 50.2 | % | ALA3375699 | % | Homo sapiens | |||
8. | ALA1354431 | SID85147395 | PPB | = | 30.1 | % | ALA3375697 | % | ||||
9. | ALA1354431 | SID85147395 | PPB | = | 18.8 | % | ALA3375696 | % | ||||
10. | ALA1354431 | SID85147395 | PPB | = | 59.4 | % | ALA3375695 | % | ||||
11. | ALA1354431 | SID85147395 | permeability | < | 4.4 | 10'-6 cm/s | ALA3375693 | 10'-6 cm/s | ||||
12. | ALA1354431 | SID85147395 | permeability | = | 18 | 10'-6 cm/s | ALA3375692 | 10'-6 cm/s | ||||
13. | ALA1354431 | SID85147395 | permeability | = | 157 | 10'-6 cm/s | ALA3375691 | 10'-6 cm/s | ||||
14. | ALA1354431 | SID85147395 | solubility | > | 27 | ug ml-1 | ALA3375690 | ug.mL-1 | ||||
15. | ALA1354431 | SID85147395 | solubility | > | 27 | ug ml-1 | ALA3375689 | ug.mL-1 | ||||
16. | ALA1354431 | SID85147395 | solubility | > | 27 | ug ml-1 | ALA3375688 | ug.mL-1 | ||||
17. | ALA1354431 | SID85147395 | IC50 | = | 3.3 | uM | ALA3375686 | 5.48 | nM | Homo sapiens | ||
18. | ALA1354431 | SID85147395 | IC50 | = | 52 | uM | ALA3375687 | 4.28 | nM | Homo sapiens | ||
19. | ALA1354431 | SID85147395 | IC50 | = | 1.1 | uM | ALA3375685 | 5.96 | nM | Homo sapiens | ||
20. | ALA1354431 | SID85147395 | Potency | 35.481 | uM | ALA2114817 | inconclusive | nM | Homo sapiens |