| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA935 | Pentamidine Isethionate | IC50 | < | 0.5 | uM | ALA5234343 | nM | Plasmodium | |||
| 2. | ALA935 | Pentamidine Isethionate | EC50 | = | 1.15 | nM | ALA4193895 | 8.94 | nM | Trypanosoma brucei brucei | ||
| 3. | ALA935 | Pentamidine Isethionate | Ratio CC50/IC50 | = | 10 | ALA4606342 | ||||||
| 4. | ALA935 | Pentamidine Isethionate | Ratio CC50/IC50 | = | 6 | ALA4606341 | ||||||
| 5. | ALA935 | Pentamidine Isethionate | Ratio CC50/IC50 | = | 7 | ALA4606340 | ||||||
| 6. | ALA935 | Pentamidine Isethionate | Ratio CC50/IC50 | = | 4 | ALA4606339 | ||||||
| 7. | ALA935 | Pentamidine Isethionate | IC50 | = | 0.62 | uM | ALA4606350 | 6.21 | nM | Leishmania tropica | ||
| 8. | ALA935 | Pentamidine Isethionate | IC50 | = | 0.96 | uM | ALA4606349 | 6.02 | nM | Leishmania major | ||
| 9. | ALA935 | Pentamidine Isethionate | IC50 | = | 0.88 | uM | ALA4606351 | 6.06 | nM | Leishmania donovani | ||
| 10. | ALA935 | Pentamidine Isethionate | CC50 | = | 5 | uM | ALA4606354 | nM | ||||
| 11. | ALA935 | Pentamidine Isethionate | CC50 | = | 6.08 | uM | ALA4606353 | nM | Mus musculus | |||
| 12. | ALA935 | Pentamidine Isethionate | IC50 | = | 1.5 | uM | ALA4606355 | 5.82 | nM | Leishmania infantum | ||
| 13. | ALA935 | Pentamidine Isethionate | Activity | = | 0 | /uL | ALA3603153 | /uL | Trypanosoma brucei brucei | |||
| 14. | ALA935 | Pentamidine Isethionate | Activity | 0 | ALA3603151 | Non-toxic | Mus musculus | |||||
| 15. | ALA935 | Pentamidine Isethionate | Activity | = | 100 | % | ALA3603149 | % | Trypanosoma brucei brucei | |||
| 16. | ALA935 | Pentamidine Isethionate | MST | > | 30 | day | ALA3603147 | day | Trypanosoma brucei brucei | |||
| 17. | ALA935 | Pentamidine Isethionate | Activity | = | 0 | /uL | ALA3602203 | /uL | Trypanosoma brucei brucei | |||
| 18. | ALA935 | Pentamidine Isethionate | Activity | = | 0 | /uL | ALA3603155 | /uL | Trypanosoma brucei brucei | |||
| 19. | ALA935 | Pentamidine Isethionate | Activity | = | 0 | /uL | ALA3603154 | /uL | Trypanosoma brucei brucei | |||
| 20. | ALA935 | Pentamidine Isethionate | Activity | = | 23.4 | /uL | ALA3603153 | /uL | Trypanosoma brucei brucei |
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