Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	mecamylamine	2a	AC50		22.39	uM	ALA3561973		inactive	nM
2.	mecamylamine	2a	AC50		1.778	uM	ALA3562119		inactive	nM
3.	mecamylamine	2a	Ac50		28.184	uM	ALA3562112		inactive	uM
4.	mecamylamine	2a	AC50		4.467	uM	ALA3562133		inactive	nM
5.	mecamylamine	2a	Ac50		22.387	uM	ALA3562085		inactive	uM
6.	mecamylamine	2a	LogD7.4		-0.84		ALA3301363
7.	mecamylamine	2a	inhibition	=	0.56	%	ALA4513082			%	Severe acute respiratory syndrome coronavirus 2
8.	mecamylamine	2a	Inhibition	=	16.11	%	ALA4495582			%	Severe acute respiratory syndrome coronavirus 2
9.	mecamylamine	2a	IC50	=	0.3	uM	ALA3615925	6.52		nM
10.	mecamylamine	2a	AC50		35.481	uM	ALA3562146		inactive	nM
11.	mecamylamine	2a	AC50		39.811	uM	ALA3562136		active	nM
12.	mecamylamine	2a	Ac50		35.481	uM	ALA3562152		active	uM
13.	mecamylamine	2a	AC50		28.184	uM	ALA3562135		inactive	nM
14.	mecamylamine	2a	Ac50		39.811	uM	ALA3562064		inactive	uM
15.	mecamylamine	2a	Ac50		1.778	uM	ALA3561990		inactive	uM
16.	mecamylamine	2a	Potency		8.492	uM	ALA3215185		inconclusive	nM	Homo sapiens
17.	mecamylamine	2a	pIC50	<	4.7		ALA4651403		No. Measurements = 1	nM	Severe acute respiratory syndrome coronavirus 2
18.	mecamylamine	2a	IC50	>	0	M	ALA4651403		No. Measurements = 1	nM	Severe acute respiratory syndrome coronavirus 2
19.	mecamylamine	2a	inhibition	=	0.56	%	ALA4513082			%	Severe acute respiratory syndrome coronavirus 2
20.	mecamylamine	2a	DILI_Concern		0		ALA4029350		No-Dili-Concern		Homo sapiens