Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA5278465	33	IC50	>	2	uM	ALA5252901		nM	Homo sapiens
2.	ALA5288565	29	IC50	>	2	uM	ALA5252901		nM	Homo sapiens
3.	ALA5270581	18	IC50	>	2	uM	ALA5252901		nM	Homo sapiens
4.	ALA4213175	Fig S3, Cpd 6	IC50	>	2	uM	ALA5252901		nM	Homo sapiens
5.	ALA3586447	11	INH	=	99.8	%	ALA5252738		%	Homo sapiens
6.	ALA3586443	7	INH	=	86	%	ALA5252738		%	Homo sapiens
7.	4-Aminocinnoline-3-carboxamide	HTS-9026	INH	=	43	%	ALA5252738		%	Homo sapiens
8.	ALA5270781	38	IC50	>	2	uM	ALA5252052		nM	Homo sapiens
9.	ALA5276374	(S)-20a; BGB-8035	INH	>	70	%	ALA5251932		%	Homo sapiens
10.	ALA5276374	(S)-20a; BGB-8035	IC50	=	4.1	nM	ALA5251910	8.39	nM	Homo sapiens
11.	ALA3932338	BDBM250054	IC50	=	15.1	nM	ALA5251905	7.82	nM	Homo sapiens
12.	tolebrutinib	TOLEBRUTINIB	IC50	=	6.2	nM	ALA5251905	8.21	nM	Homo sapiens
13.	Branebrutinib (BMS-986195)	BRANEBRUTINIB	IC50	=	1.2	nM	ALA5251905	8.92	nM	Homo sapiens
14.	Evobrutinib (M-2951)	Evobrutinib	IC50	=	22	nM	ALA5251905	7.66	nM	Homo sapiens
15.	tirabrutinib	TIRABRUTINIB	IC50	=	29	nM	ALA5251905	7.54	nM	Homo sapiens
16.	Orelabrutinib (ICP-022)	ORELABRUTINIB	IC50	=	20	nM	ALA5251905	7.70	nM	Homo sapiens
17.	Acalabrutinib (ACP-196)	ACALABRUTINIB	IC50	=	11	nM	ALA5251905	7.96	nM	Homo sapiens
18.	Ibrutinib (PCI-32765)	SID124898784	IC50	=	6.3	nM	ALA5251905	8.20	nM	Homo sapiens
19.	ALA5272404	36	IC50	=	20.3	nM	ALA5251905	7.69	nM	Homo sapiens
20.	ALA5282956	35	IC50	=	21.9	nM	ALA5251905	7.66	nM	Homo sapiens