| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA301982 | 1 | Ki | = | 7.05 | uM | ALA5233908 | 5.15 | nM | Rattus norvegicus | ||
| 2. | ALA301982 | 1 | IC50 | = | 10.2 | uM | ALA5233907 | 4.99 | nM | Rattus norvegicus | ||
| 3. |  ALA4288347 | 2; K-604 | Drug metabolism | 0 | ALA4725832 | Metabolite_Notdetected | Rattus norvegicus | |||||
| 4. |  Cannabidiol | 3 | Ki | = | 20.7 | uM | ALA4687731 | 4.68 | nM | Rattus norvegicus | ||
| 5. |  ALA3526190 | DB868 | Drug metabolism | 0 | ALA3530927 | metabolite_not_detected | Rattus norvegicus | |||||
| 6. | ALA3526190 | DB868 | Drug metabolism | 0 | ALA3530781 | metabolite_not_detected | Rattus norvegicus | |||||
| 7. |  Arteether | Beta-arteether | IC50 | > | 100 | uM | ALA2328459 | nM | Rattus norvegicus | |||
| 8. |  ALA1200689 | NITRIC OXIDE | mechanism based inhibition | 0 | ALA1908268 | Cytochrome P450 mechanistic inhibitor: PMID 9400024 | Rattus norvegicus | |||||
| 9. |  Cimetidine | cimetidine | mechanism based inhibition | 0 | ALA1908267 | Cytochrome P450 mechanistic inhibitor: PMID 1545403 | Rattus norvegicus | |||||
| 10. |  Chloramphenicol | 6 | mechanism based inhibition | 0 | ALA1908266 | Cytochrome P450 mechanistic inhibitor: PMID 7932191 | Rattus norvegicus | |||||
| 11. |  Nortriptyline | nortriptyline | mechanism based inhibition | 0 | ALA1908269 | Cytochrome P450 mechanistic inhibitor: PMID 14555335 | Rattus norvegicus | |||||
| 12. | Nortriptyline | nortriptyline | mechanism based inhibition | 0 | ALA1908269 | Cytochrome P450 mechanistic inhibitor: PMID 1435757 | Rattus norvegicus | |||||
| 13. |  nisoxetine | 12 (Nisoxetine) | mechanism based inhibition | 0 | ALA1908269 | Cytochrome P450 mechanistic inhibitor: PMID 14555335 | Rattus norvegicus | |||||
| 14. |  Fluoxetine | fluoxetine | mechanism based inhibition | 0 | ALA1908269 | Cytochrome P450 mechanistic inhibitor: PMID 14555335 | Rattus norvegicus | |||||
| 15. |  desipramine | desmethylimipramine | mechanism based inhibition | 0 | ALA1908269 | Cytochrome P450 mechanistic inhibitor: PMID 14555335 | Rattus norvegicus | |||||
| 16. |  ALA157101 | ketoconazole | IC50 | = | 104.3 | uM | ALA615199 | nM | Rattus norvegicus | |||
| 17. |  (2S,4S)-ketoconazole | 5 | IC50 | = | 34.3 | uM | ALA615199 | 4.46 | nM | Rattus norvegicus | ||
| 18. |  rac-trans-Ketoconazole | 3 | IC50 | = | 20.4 | uM | ALA615199 | 4.69 | nM | Rattus norvegicus | ||
| 19. | ALA157101 | ketoconazole | IC50 | = | 84.1 | uM | ALA615199 | 4.08 | nM | Rattus norvegicus |
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