# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Sulbactam | 1 | MIC | = | 1.56 | ug ml-1 | ALA4377161 | ug.mL-1 | Staphylococcus aureus | |||
2. | ALA3914769 | 6a | INH | 0 | ALA3877838 | % | Staphylococcus aureus | |||||
3. | ALA4170126 | 12d | FICI | = | 0.2 | ALA4139274 | Staphylococcus aureus | |||||
4. | ALA4164703 | 5 | FICI | = | 0.2 | ALA4139274 | Staphylococcus aureus | |||||
5. | ALA4170126 | 12d | MIC | = | 0.9 | ug ml-1 | ALA4139270 | ug.mL-1 | Staphylococcus aureus | |||
6. | ALA4164703 | 5 | MIC | = | 0.8 | ug ml-1 | ALA4139270 | ug.mL-1 | Staphylococcus aureus | |||
7. | ALA4170126 | 12d | INH | 0 | ALA4139264 | Not Active | % | Staphylococcus aureus | ||||
8. | ALA4164703 | 5 | INH | 0 | ALA4139264 | Not Active | % | Staphylococcus aureus | ||||
9. | ALA4170126 | 12d | INH | 0 | ALA4139263 | Active | % | Staphylococcus aureus | ||||
10. | ALA4164703 | 5 | INH | 0 | ALA4139263 | Active | % | Staphylococcus aureus | ||||
11. | ALA71598 | 14g | Relative protection | = | 0.9 | ALA655124 | Staphylococcus aureus | |||||
12. | ALA306161 | 28h | Relative protection | = | 0.2 | ALA655124 | Staphylococcus aureus | |||||
13. | ALA70933 | 28f | Relative protection | = | 0.3 | ALA655124 | Staphylococcus aureus | |||||
14. | ALA71822 | 11g | Relative protection | = | 0.7 | ALA655124 | Staphylococcus aureus | |||||
15. | ALA73453 | 14j | Relative protection | = | 1.9 | ALA655124 | Staphylococcus aureus | |||||
16. | ALA74235 | 28i | Relative protection | = | 0.2 | ALA655124 | Staphylococcus aureus | |||||
17. | ALA307959 | 13i | Relative protection | = | 2.7 | ALA655124 | Staphylococcus aureus | |||||
18. | ALA1626995 | 28k | Relative protection | < | 0.1 | ALA655124 | Staphylococcus aureus | |||||
19. | penicillin G | Benzylpenicillin | Kcat | = | 65 | /s | ALA986867 | /s | Staphylococcus aureus | |||
20. | ceftobiprole | BPR, ceftobiprole | Km | = | 78 | uM | ALA986867 | nM | Staphylococcus aureus |