# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3775576 | 18 | Activity | = | 8 | % | ALA3778884 | % | Homo sapiens | |||
2. | ALA3774885 | 39 | Activity | = | -6 | % | ALA3778884 | % | Homo sapiens | |||
3. | ALA3775317 | 31 | Activity | = | 19 | % | ALA3778884 | % | Homo sapiens | |||
4. | ALA3758502 | 1 | INH | = | 0.1 | % | ALA3761207 | % | Homo sapiens | |||
5. | ALA3745885 | 7ao; ON1231320 | IC50 | > | 10 | uM | ALA3750180 | nM | Homo sapiens | |||
6. | ALA3746293 | 23 | IC50 | = | 230 | nM | ALA3750473 | 6.64 | nM | Homo sapiens | ||
7. | ALA3746293 | 23 | INH | = | 87.9 | % | ALA3749826 | % | Homo sapiens | |||
8. | ALA3732311 | P-0002 | IC50 | <= | 10 | uM | ALA3734117 | nM | Homo sapiens | |||
9. | ALA3728149 | P-0004 | IC50 | <= | 10 | uM | ALA3734117 | nM | Homo sapiens | |||
10. | ALA3628628 | 5 | INH | = | 5.53 | % | ALA3631494 | % | Homo sapiens | |||
11. | ALA3628627 | 4 | INH | = | 89.15 | % | ALA3631494 | % | Homo sapiens | |||
12. | ALA166031 | 3 | INH | = | 3.88 | % | ALA3631494 | % | Homo sapiens | |||
13. | ALA3622193 | 34 | IC50 | = | 41 | nM | ALA3627426 | 7.39 | nM | Homo sapiens | ||
14. | ALA3621515 | 25 | IC50 | = | 162 | nM | ALA3627426 | 6.79 | nM | Homo sapiens | ||
15. | ALA3621496 | 6 | IC50 | = | 116 | nM | ALA3627426 | 6.94 | nM | Homo sapiens | ||
16. | ALA5288888 | 56 | INH | > | 20 | % | ALA5255165 | % | Homo sapiens | |||
17. | ALA5278465 | 33 | IC50 | > | 2 | uM | ALA5252930 | nM | Homo sapiens | |||
18. | tolebrutinib | TOLEBRUTINIB | IC50 | = | 7.8 | nM | ALA5251929 | 8.11 | nM | Homo sapiens | ||
19. | Branebrutinib (BMS-986195) | BRANEBRUTINIB | IC50 | = | 1.1 | nM | ALA5251929 | 8.96 | nM | Homo sapiens | ||
20. | Evobrutinib (M-2951) | Evobrutinib | IC50 | = | 20 | nM | ALA5251929 | 7.70 | nM | Homo sapiens |