| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA3758502 | 1 | INH | = | 61.5 | % | ALA3761274 | % | Homo sapiens | |||
| 2. |  ALA3745885 | 7ao; ON1231320 | IC50 | > | 10 | uM | ALA3750195 | nM | Homo sapiens | |||
| 3. |  ALA3746293 | 23 | INH | = | -4.7 | % | ALA3751278 | % | Homo sapiens | |||
| 4. |  ALA3633152 | 24 | Kd | = | 410 | nM | ALA3635834 | 6.39 | nM | Homo sapiens | ||
| 5. |  ALA3628628 | 5 | INH | = | 27.75 | % | ALA3631614 | % | Homo sapiens | |||
| 6. |  ALA3628627 | 4 | INH | = | 97.46 | % | ALA3631614 | % | Homo sapiens | |||
| 7. |  ALA166031 | 3 | INH | = | 24.76 | % | ALA3631614 | % | Homo sapiens | |||
| 8. |  ALA3622193 | 34 | IC50 | = | 95 | nM | ALA3627427 | 7.02 | nM | Homo sapiens | ||
| 9. |  ALA3621515 | 25 | IC50 | = | 172 | nM | ALA3627427 | 6.76 | nM | Homo sapiens | ||
| 10. |  ALA3621496 | 6 | IC50 | = | 119 | nM | ALA3627427 | 6.92 | nM | Homo sapiens | ||
| 11. |  ALA5288888 | 56 | INH | > | 20 | % | ALA5255164 | % | Homo sapiens | |||
| 12. |  ALA5270781 | 38 | IC50 | > | 2 | uM | ALA5252063 | nM | Homo sapiens | |||
| 13. |  ALA3932338 | BDBM250054 | IC50 | = | 34 | nM | ALA5251911 | 7.47 | nM | Homo sapiens | ||
| 14. |  ALA5276374 | (S)-20a; BGB-8035 | IC50 | = | 3.4 | nM | ALA5251911 | 8.47 | nM | Homo sapiens | ||
| 15. |  ALA5274179 | 41 | INH | 0 | ALA5240398 | Not Active | % | Homo sapiens | ||||
| 16. |  mobocertinib | MOBOCERTINIB | INH | > | 81 | % | ALA5238874 | % | Homo sapiens | |||
| 17. |  Selitrectinib (LOXO-195) | SELITRECTINIB | % of control | = | 14 | % | ALA5213059 | % | Homo sapiens | |||
| 18. |  Acalabrutinib (ACP-196) | ACALABRUTINIB | IC50 | = | 368 | nM | ALA5213055 | 6.43 | nM | Homo sapiens | ||
| 19. |  Zanubrutinib (BGB-3111) | BDBM250082 | IC50 | = | 2.95 | nM | ALA5210355 | 8.53 | nM | Homo sapiens | ||
| 20. | Zanubrutinib (BGB-3111) | BDBM250082 | IC50 | = | 360 | nM | ALA5209940 | 6.44 | nM | Homo sapiens |
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