Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	Gambogic acid	1, GA	IC50	=	2.02	uM	ALA5241838	5.70		nM	Homo sapiens
2.	ABT-199 (GDC-0199)	VENETOCLAX	Ki	=	245	nM	ALA5234934	6.61		nM	Homo sapiens
3.	ALA443684	Scheme 4, 11	Ki	<=	1	nM	ALA5234930			nM	Homo sapiens
4.	ABT-199 (GDC-0199)	VENETOCLAX	Ki	=	245	nM	ALA5163774	6.61		nM	Homo sapiens
5.	3-Chloro-1-(3,4-dichlorophenyl)-4-(4-methylpiperazin-1-yl)pyrrole-2,5-dione	1	Ki	=	12.5	uM	ALA5163774	4.90		nM	Homo sapiens
6.	ALA443684	Scheme 4, 11	IC50	=	0.07	uM	ALA4409526	7.16		nM	Homo sapiens
7.	ALA4474764	13	IC50	=	4.37	uM	ALA4409526	5.36		nM	Homo sapiens
8.	ALA4560892	12	IC50	=	21	uM	ALA4409526	4.68		nM	Homo sapiens
9.	ALA4446373	11	IC50	=	59.1	uM	ALA4409526	4.23		nM	Homo sapiens
10.	ALA4592905	10	IC50	=	1	uM	ALA4409526	6.00		nM	Homo sapiens
11.	ALA4584015	9	IC50	=	12.5	uM	ALA4409526	4.90		nM	Homo sapiens
12.	ALA4473013	8	IC50	=	4.01	uM	ALA4409526	5.40		nM	Homo sapiens
13.	ALA4529727	7	IC50	=	14.5	uM	ALA4409526	4.84		nM	Homo sapiens
14.	ALA4437855	4	IC50		0		ALA4409526		Not Determined		Homo sapiens
15.	ALA4464321	3	IC50		0		ALA4409526		Not Determined		Homo sapiens
16.	ALA4524407	2	IC50		0		ALA4409526		Not Determined		Homo sapiens
17.	4-(4-Fluorophenyl)benzoic acid	16	IC50		0		ALA4409526		Not Determined		Homo sapiens
18.	ABT-737	2, ABT-737	Ki	=	285	nM	ALA4398458	6.54		nM	Homo sapiens
19.	ALA551288	2, Apogossypol	Ki	=	2100	nM	ALA4398458	5.68		nM	Homo sapiens
20.	ALA408194	obatoclax, GX15-070	Ki	=	7010	nM	ALA4398458	5.15		nM	Homo sapiens