# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA3087342 | 25 | CL | = | 0.16 | L/hr/kg | ALA3088688 | mL.min-1.kg-1 | Macaca fascicularis | |||
2. | ALA3087342 | 25 | Vdss | = | 3.1 | L/Kg | ALA3088687 | L.kg-1 | Macaca fascicularis | |||
3. | ALA3087342 | 25 | t1/2 | = | 15.9 | hr | ALA3088686 | hr | Macaca fascicularis | |||
4. | ALA3087342 | 25 | F | = | 56 | % | ALA3088685 | % | Macaca fascicularis | |||
5. | oliceridine | (R)-30, TRV130 | Activity | 0 | ALA2445745 | Non-toxic | Macaca fascicularis | |||||
6. | oliceridine | (R)-30, TRV130 | Activity | 0 | ALA2445744 | Non-toxic | Macaca fascicularis | |||||
7. | oliceridine | (R)-30, TRV130 | Activity | 0 | ALA2445742 | Non-toxic | Macaca fascicularis | |||||
8. | oliceridine | (R)-30, TRV130 | Activity | 0 | ALA2445743 | Non-toxic | Macaca fascicularis | |||||
9. | ALA2441636 | 5a(SS), SAR110068 | Activity | 0 | ALA2443501 | Non-toxic | Macaca fascicularis | |||||
10. | ALA2441636 | 5a(SS), SAR110068 | Activity | 0 | ALA2443502 | Non-toxic | Macaca fascicularis | |||||
11. | ALA2442537 | 9 | Drug metabolism | = | 35 | % | ALA2447772 | % | Macaca fascicularis | |||
12. | ALA2442537 | 9 | Drug metabolism | = | 10 | % | ALA2447771 | % | Macaca fascicularis | |||
13. | ALA2442537 | 9 | Stability | = | 75 | % | ALA2447770 | % | Macaca fascicularis | |||
14. | ALA2023193 | 6 | Stability | = | 55 | % | ALA2447769 | % | Macaca fascicularis | |||
15. | ALA2442537 | 9 | Stability | = | 50 | % | ALA2447769 | % | Macaca fascicularis | |||
16. | ALA2023193 | 6 | Stability | = | 35 | % | ALA2447768 | % | Macaca fascicularis | |||
17. | ALA2442537 | 9 | Stability | = | 20 | % | ALA2447768 | % | Macaca fascicularis | |||
18. | ALA2442537 | 9 | Drug recovery | > | 95 | % | ALA2447767 | % | Macaca fascicularis | |||
19. | ALA2442537 | 9 | Retention_time | = | 2.9 | min | ALA2447766 | min | Macaca fascicularis | |||
20. | ALA2442537 | 9 | Retention_time | = | 6.7 | min | ALA2447765 | min | Macaca fascicularis |