Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4475665	Example 36	IC50	=	325	nM	ALA4367206	6.49		nM	Mus musculus
2.	1-[(1R)-1-(2,4-Dichlorophenyl)ethyl]-6-[(4S,5R)-4-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-5-methylcyclohexen-1-yl]pyrazolo[3,4-b]pyrazine-3-carbonitrile	Example 31	IC50	=	165	nM	ALA4367206	6.78		nM	Mus musculus
3.	ALA4637143	38	IC50	=	39	nM	ALA4630459	7.41		nM	Mus musculus
4.	ALA4172635	49	pIC50	=	9		ALA4134304	9.00		nM	Mus musculus
5.	AZD 2098	47	pIC50	=	8		ALA4134304	8.00		nM	Mus musculus
6.	ALA2011441	G	pIC50	=	8.3		ALA4134304	8.30		nM	Mus musculus
7.	ALA459463	14e	Activity	=	0.21	uM	ALA946420			uM	Mus musculus
8.	ALA516936	14f	Activity	=	0.8	uM	ALA946420			uM	Mus musculus
9.	ALA459464	14g	Activity	=	0.22	uM	ALA946420			uM	Mus musculus
10.	ALA459465	14h	Activity		0		ALA946420		Not Determined		Mus musculus
11.	ALA515355	20	Activity		0		ALA946420		Not Determined		Mus musculus
12.	ALA487635	C-006, 5	Activity	=	0.13	uM	ALA946420			uM	Mus musculus
13.	N-cycloheptyl-6,7-dimethoxy-2-(4-piperidin-1-ylpiperidin-1-yl)quinazolin-4-amine	C-021, 14a	Activity	=	0.039	uM	ALA946420			uM	Mus musculus
14.	ALA509396	C-030, 14c	Activity	=	0.29	uM	ALA946420			uM	Mus musculus
15.	ALA453594	14b	Activity	=	0.6	uM	ALA946420			uM	Mus musculus
16.	ALA451783	14d	Activity	=	0.35	uM	ALA946420			uM	Mus musculus
17.	ALA499592	8c	IC50		0		ALA1020786		Not Determined		Mus musculus
18.	ALA496787	8ie	INH	=	50	%	ALA1020800			%	Mus musculus
19.	ALA518386	8n	IC50		0		ALA1020786		Not Determined		Mus musculus
20.	ALA463722	8m	IC50		0		ALA1020786		Not Determined		Mus musculus