# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | A 366 | 12, A-366 | EC50 | > | 50 | uM | ALA5214727 | nM | Homo sapiens | |||
2. | UNC 0642 | 7, UNC0642 | IC50 | > | 10 | uM | ALA5214614 | nM | Homo sapiens | |||
3. | SGC 0946 | 24, SGC0946 | IC50 | > | 100 | uM | ALA5214637 | nM | Homo sapiens | |||
4. | (R)-PFI 2 hydrochloride | EUB0000196bCl | Kd | = | 4.2 | nM | ALA5214696 | 8.38 | nM | Homo sapiens | ||
5. | (R)-PFI 2 hydrochloride | EUB0000196bCl | Kd | = | 18 | nM | ALA5214695 | 7.75 | nM | Homo sapiens | ||
6. | OICR-9429 | 16d; OICR-9429 | % activity remaining | > | 90 | % | ALA5213713 | % | Homo sapiens | |||
7. | (R)-PFI 2 hydrochloride | EUB0000196bCl | IC50 | = | 2 | nM | ALA5210605 | 8.70 | nM | Homo sapiens | ||
8. | (R)-PFI 2 hydrochloride | EUB0000196bCl | EC50 | < | 10000 | nM | ALA5210297 | nM | Homo sapiens | |||
9. | ALA5195436 | 9; MS159 | INH | 0 | ALA5141713 | NA | % | Homo sapiens | ||||
10. | ALA5173678 | 12h; EML981 | INH | 0 | ALA5138960 | NA | % | Homo sapiens | ||||
11. | ALA4640116 | DC21 | IC50 | = | 15.93 | uM | ALA5138488 | 4.80 | nM | Homo sapiens | ||
12. | ALA3623770 | DC-S238 | IC50 | = | 4.88 | uM | ALA5138231 | 5.31 | nM | Homo sapiens | ||
13. | ALA4640116 | DC21 | IC50 | = | 15.93 | uM | ALA5138231 | 4.80 | nM | Homo sapiens | ||
14. | ALA5197135 | 49 | IC50 | > | 10 | uM | ALA5138231 | nM | Homo sapiens | |||
15. | ALA5184605 | 6 | IC50 | = | 2.5 | uM | ALA5138231 | 5.60 | nM | Homo sapiens | ||
16. | ALA5170450 | 8; MS8511 | INH | > | 50 | % | ALA5129705 | % | Homo sapiens | |||
17. | Ibiglustat | VENGLUSTAT | INH | = | 50 | % | ALA5119889 | % | Homo sapiens | |||
18. | Ibiglustat | VENGLUSTAT | INH | 0 | ALA5119851 | NA | % | Homo sapiens | ||||
19. | Ibiglustat | VENGLUSTAT | INH | 0 | ALA5119822 | NA | % | Homo sapiens | ||||
20. | Dot1L-IN-4 | 10 | INH | 0 | ALA4411208 | Not Active | % | Homo sapiens |