# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Lorlatinib | 8k, PF-06463922 | Ki | = | 14 | nM | ALA5213169 | 7.85 | nM | Homo sapiens | ||
2. | MPS1-IN-1 | Mps1-IN-1 | IC50 | = | 280 | nM | ALA5212781 | 6.55 | nM | Homo sapiens | ||
3. | MPS1-IN-1 | Mps1-IN-1 | % of control | = | 0.5 | % | ALA5212780 | % | Homo sapiens | |||
4. | Defactinib | DEFACTINIB | IC50 | = | 0.2 | nM | ALA5210429 | 9.70 | nM | Homo sapiens | ||
5. | ALA4518706 | EUB0000702 | IC50 | = | 721 | nM | ALA5210417 | 6.14 | nM | Homo sapiens | ||
6. | ALA4445335 | Roxyl-ZV-5J | INH | = | 73 | % | ALA4408110 | % | Homo sapiens | |||
7. | ALA4455923 | 48c | INH | < | 50 | % | ALA4405540 | % | Homo sapiens | |||
8. | ALA4559936 | (+/-)-6 | Activity | = | 74 | % | ALA4391551 | % | Homo sapiens | |||
9. | ALA4564973 | 50 | INH | = | 84 | % | ALA4389925 | % | Homo sapiens | |||
10. | ALA4555459 | 43 | INH | = | 96 | % | ALA4389448 | % | Homo sapiens | |||
11. | ALA4473365 | 7c | Activity | = | 0.5 | % | ALA4382729 | % | Homo sapiens | |||
12. | ALA4438748 | 12j | IC50 | > | 10 | uM | ALA4379414 | nM | Homo sapiens | |||
13. | CDK9-IN-7 | 21e | INH | = | 46 | % | ALA4377839 | % | Homo sapiens | |||
14. | ALA4462318 | 19i | Kd(free) | = | 6.928 | uM | ALA4371459 | 5.16 | nM | Homo sapiens | ||
15. | Dasatinib | 2, BMS-354825 | Activity | > | 75 | % | ALA4807980 | % | Homo sapiens | |||
16. | ALA4855726 | B3 | Activity | > | 75 | % | ALA4807980 | % | Homo sapiens | |||
17. | ALA4867844 | C7 | Activity | > | 75 | % | ALA4807980 | % | Homo sapiens | |||
18. | ALA2348350 | 15u | Activity | = | 84 | % | ALA4806738 | % | Homo sapiens | |||
19. | ALA2348350 | 15u | Activity | = | 97 | % | ALA4806738 | % | Homo sapiens | |||
20. | Meisoindigo | 2 | Activity | = | 100 | % | ALA4806176 | % | Homo sapiens |