Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5276737	HL2-m5	Kd	=	170	nM	ALA5250709	6.77		nM	Homo sapiens
2.	Robotnikinin	2	Kd	=	3.1	uM	ALA4321981	5.51		nM	Homo sapiens
3.	Vismodegib (GDC-0449)	101, GDC-0449	INH		0		ALA1777114		Not Active	%	Homo sapiens
4.	Vismodegib (GDC-0449)	101, GDC-0449	INH		0		ALA1776929		Active	%	Homo sapiens
5.	Vismodegib (GDC-0449)	101, GDC-0449	IC50	=	1750	nM	ALA1776928	5.76		nM	Homo sapiens
6.	Vismodegib (GDC-0449)	101, GDC-0449	IC50	=	15	nM	ALA1776927	7.82		nM	Homo sapiens
7.	ALA1221983	2, SAG	Activity		0		ALA2162668		Dose-dependent effect		Homo sapiens
8.	ALA2160035	10g	Activity		0		ALA2162668		Dose-dependent effect		Homo sapiens
9.	ALA2160033	10e	Activity		0		ALA2162668		Dose-dependent effect		Homo sapiens
10.	ALA2160031	10c	Activity		0		ALA2162668		Dose-dependent effect		Homo sapiens
11.	ALA1221983	2, SAG	FC	=	7		ALA2162669				Homo sapiens
12.	ALA2160035	10g	FC	=	7		ALA2162669				Homo sapiens
13.	ALA2160033	10e	FC	=	7		ALA2162669				Homo sapiens
14.	ALA2160031	10c	FC	=	7		ALA2162669				Homo sapiens
15.	ALA1221983	2, SAG	Activity	=	29.61	pg/ml	ALA2162670			pg/ml	Homo sapiens
16.	ALA2160031	10c	Activity	=	32.44	pg/ml	ALA2162671			pg/ml	Homo sapiens
17.	ALA2160033	10e	Activity	=	23.83	pg/ml	ALA2162671			pg/ml	Homo sapiens
18.	ALA2160035	10g	Activity	=	32.22	pg/ml	ALA2162671			pg/ml	Homo sapiens
19.	Cyclopamine	1	IC50	=	0.6	uM	ALA2155375	6.22		nM	Homo sapiens
20.	Robotnikinin	2	Imax	=	47	%	ALA2155376			%	Homo sapiens