# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Thiamine pyrophosphate | COCARBOXYLASE | Kd | = | 3.1 | uM | ALA3380663 | 5.51 | nM | Mycobacterium tuberculosis | ||
2. | ALA3305928 | 10 | Ki | = | 4 | uM | ALA3380657 | 5.40 | nM | Mycobacterium tuberculosis | ||
3. | ALA490176 | 6 | IC50 | = | 71.1 | uM | ALA989742 | 4.15 | nM | Mycobacterium tuberculosis | ||
4. | ALA1486536 | 7 | IC50 | = | 23 | uM | ALA989742 | 4.64 | nM | Mycobacterium tuberculosis | ||
5. | ALA521577 | 8 | IC50 | = | 14 | uM | ALA989742 | 4.85 | nM | Mycobacterium tuberculosis | ||
6. | ALA1509762 | 9 | IC50 | = | 20.2 | uM | ALA989742 | 4.70 | nM | Mycobacterium tuberculosis | ||
7. | ALA491398 | 10 | IC50 | = | 73 | uM | ALA989742 | 4.14 | nM | Mycobacterium tuberculosis | ||
8. | ALA491399 | 12 | IC50 | = | 98.4 | uM | ALA989742 | 4.01 | nM | Mycobacterium tuberculosis | ||
9. | ALA522583 | 15 | IC50 | = | 90.7 | uM | ALA989742 | 4.04 | nM | Mycobacterium tuberculosis | ||
10. | ALA505602 | 16 | IC50 | = | 42.4 | uM | ALA989742 | 4.37 | nM | Mycobacterium tuberculosis | ||
11. | ALA489164 | 17 | IC50 | = | 34.2 | uM | ALA989742 | 4.47 | nM | Mycobacterium tuberculosis | ||
12. | ALA491607 | 18 | IC50 | = | 10.9 | uM | ALA989742 | 4.96 | nM | Mycobacterium tuberculosis | ||
13. | ALA491210 | 19 | IC50 | = | 10.6 | uM | ALA989742 | 4.97 | nM | Mycobacterium tuberculosis | ||
14. | ALA522461 | 20 | IC50 | = | 53.5 | uM | ALA989742 | 4.27 | nM | Mycobacterium tuberculosis | ||
15. | ALA491211 | 21 | IC50 | = | 30.6 | uM | ALA989742 | 4.51 | nM | Mycobacterium tuberculosis | ||
16. | ALA489785 | 22 | IC50 | = | 55.1 | uM | ALA989742 | 4.26 | nM | Mycobacterium tuberculosis | ||
17. | ALA521592 | 23 | IC50 | = | 41.4 | uM | ALA989742 | 4.38 | nM | Mycobacterium tuberculosis | ||
18. | ALA488964 | 24 | IC50 | = | 63.7 | uM | ALA989742 | 4.20 | nM | Mycobacterium tuberculosis | ||
19. | ALA491216 | 26 | IC50 | = | 19.5 | uM | ALA989742 | 4.71 | nM | Mycobacterium tuberculosis | ||
20. | ALA522627 | 27 | IC50 | = | 17.9 | uM | ALA989742 | 4.75 | nM | Mycobacterium tuberculosis |