# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA2236666 | LN-1255 | Ki | = | 4.23 | uM | ALA3061793 | 5.37 | nM | Klebsiella pneumoniae | ||
2. | ALA1673091 | penem 1 | Ki | = | 109.86 | uM | ALA3061793 | nM | Klebsiella pneumoniae | |||
3. | ALA1673092 | penem 2 | Ki | = | 67.89 | uM | ALA3061793 | 4.17 | nM | Klebsiella pneumoniae | ||
4. | clavulanic acid | Clavulanic acid | Ki | = | 229.1 | uM | ALA3061793 | nM | Klebsiella pneumoniae | |||
5. | vaborbactam | 27, RPX7009 | MIC | = | 0.13 | ug ml-1 | ALA3579494 | ug.mL-1 | Klebsiella pneumoniae | |||
6. | vaborbactam | 27, RPX7009 | MIC | = | 0.13 | ug ml-1 | ALA3579492 | ug.mL-1 | Klebsiella pneumoniae | |||
7. | vaborbactam | 27, RPX7009 | MIC | <= | 0.06 | ug ml-1 | ALA3579170 | ug.mL-1 | Klebsiella pneumoniae | |||
8. | vaborbactam | 27, RPX7009 | MIC | <= | 0.06 | ug ml-1 | ALA3579172 | ug.mL-1 | Klebsiella pneumoniae | |||
9. | vaborbactam | 27, RPX7009 | MIC | <= | 0.06 | ug ml-1 | ALA3578636 | ug.mL-1 | Klebsiella pneumoniae | |||
10. | vaborbactam | 27, RPX7009 | MIC | <= | 0.06 | ug ml-1 | ALA3579471 | ug.mL-1 | Klebsiella pneumoniae | |||
11. | vaborbactam | 27, RPX7009 | MIC | <= | 0.06 | ug ml-1 | ALA3579654 | ug.mL-1 | Klebsiella pneumoniae | |||
12. | vaborbactam | 27, RPX7009 | MIC | <= | 0.06 | ug ml-1 | ALA3579656 | ug.mL-1 | Klebsiella pneumoniae | |||
13. | Cephalothin | Cephalothin | Km | = | 40 | uM | ALA1263489 | nM | Klebsiella pneumoniae | |||
14. | clavulanic acid | Clavulanic acid | IC50 | = | 0.17 | uM | ALA1263490 | 6.77 | nM | Klebsiella pneumoniae | ||
15. | Cefepime | 82(Cefepime) | Kcat/Km | 0 | ALA1263487 | Not Determined | Klebsiella pneumoniae | |||||
16. | ALA158 | aztreonam | Kcat/Km | 0 | ALA1263487 | Not Determined | Klebsiella pneumoniae | |||||
17. | Cefotaxime acid | cefotaxime | Kcat/Km | 0 | ALA1263487 | Not Determined | Klebsiella pneumoniae | |||||
18. | Ceftazidime | CAZ | Kcat/Km | 0 | ALA1263487 | Not Determined | Klebsiella pneumoniae | |||||
19. | ALA1436 | Cefuroxime | Kcat/Km | 0 | ALA1263487 | Not Determined | Klebsiella pneumoniae | |||||
20. | Piperacillin | Piperacillin | Kcat/Km | = | 62.5 | /uM/s | ALA1263487 | /uM/s | Klebsiella pneumoniae |