# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Orlistat | 1 (orlistat) | INH | 0 | ALA3373890 | Dose-dependent effect | % | Mus musculus | ||||
2. | ALA3319622 | 17 | INH | 0 | ALA3373890 | Dose-dependent effect | % | Mus musculus | ||||
3. | ALA3319620 | 15, LEI-106 | INH | 0 | ALA3373890 | Dose-dependent effect | % | Mus musculus | ||||
4. | ALA3319619 | 14 | INH | 0 | ALA3373890 | Dose-dependent effect | % | Mus musculus | ||||
5. | ALA3319622 | 17 | IC50 | = | 743 | nM | ALA3373888 | 6.13 | nM | Mus musculus | ||
6. | ALA3319620 | 15, LEI-106 | IC50 | = | 124 | nM | ALA3373888 | 6.91 | nM | Mus musculus | ||
7. | ALA3319619 | 14 | IC50 | = | 355 | nM | ALA3373888 | 6.45 | nM | Mus musculus | ||
8. | Orlistat | 1 (orlistat) | INH | 0 | ALA3373888 | Dose-dependent effect | % | Mus musculus | ||||
9. | ALA3319622 | 17 | INH | 0 | ALA3373888 | Dose-dependent effect | % | Mus musculus | ||||
10. | ALA3319619 | 14 | INH | 0 | ALA3373888 | Dose-dependent effect | % | Mus musculus | ||||
11. | ALA3319620 | 15, LEI-106 | INH | 0 | ALA3373888 | Dose-dependent effect | % | Mus musculus | ||||
12. | ALA3319620 | 15, LEI-106 | pIC50 | = | 6.9 | ALA4427018 | 6.90 | nM | Mus musculus | |||
13. | LEI105 | LEI105 | pIC50 | = | 7.6 | ALA4427018 | 7.60 | nM | Mus musculus | |||
14. | PHOP | 7 | pIC50 | = | 6.3 | ALA4427018 | 6.30 | nM | Mus musculus | |||
15. | ALA4572363 | 4 | IC50 | = | 0.21 | uM | ALA4376250 | 6.68 | nM | Mus musculus | ||
16. | ALA4532055 | 3 | IC50 | = | 3.4 | uM | ALA4376250 | 5.47 | nM | Mus musculus | ||
17. | LEI105 | LEI105 | Ki | = | 0.23 | nM | ALA4376251 | 9.64 | nM | Mus musculus | ||
18. | LEI105 | LEI105 | pIC50 | = | 8.6 | ALA4376250 | 8.60 | nM | Mus musculus | |||
19. | KT-109 | SID125269108 | Kinact | = | 0.08 | /min | ALA4376252 | /min | Mus musculus | |||
20. | KT-109 | SID125269108 | Ki | = | 0.35 | nM | ALA4376251 | 9.46 | nM | Mus musculus |