Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	LDC1267	7; LDC1267	% of control	<	10	%	ALA5212927		%	Homo sapiens
2.	(4R)-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-2-(pyrimidin-5-yl)-1,2,3,4-tetrahydroisoquinoline-7-carboxamide	6	Kd	=	530	nM	ALA5213568	6.28	nM	Homo sapiens
3.	BMS-777607	10, BMS-777607	% of control	=	0	%	ALA5212872		%	Homo sapiens
4.	ALA5201248	38	INH	=	32	%	ALA5157188		%	Homo sapiens
5.	(4R)-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-2-(pyrimidin-5-yl)-1,2,3,4-tetrahydroisoquinoline-7-carboxamide	6	Kd	=	530	nM	ALA4425831	6.28	nM	Homo sapiens
6.	ALA4458300	4	Activity	=	90	%	ALA4414213		%	Homo sapiens
7.	ALA4462082	2	Activity	=	62	%	ALA4414213		%	Homo sapiens
8.	ALA4455923	48c	INH	<	50	%	ALA4405475		%	Homo sapiens
9.	ALA4559936	(+/-)-6	Activity	=	49	%	ALA4391460		%	Homo sapiens
10.	ALA4564973	50	INH	=	100	%	ALA4389834		%	Homo sapiens
11.	ALA4555459	43	INH	=	97	%	ALA4389357		%	Homo sapiens
12.	ALA4545456	24	INH	=	10.5	%	ALA4387308		%	Homo sapiens
13.	Abemaciclib	ABEMACICLIB	INH	=	24.8	%	ALA4387308		%	Homo sapiens
14.	ALA4473365	7c	Activity	=	92	%	ALA4382638		%	Homo sapiens
15.	ALA4438748	12j	IC50	>	10	uM	ALA4379240		nM	Homo sapiens
16.	ALA4459587	DC-TEADin02	INH	=	-12	%	ALA4378911		%	Homo sapiens
17.	CDK9-IN-7	21e	INH	=	66	%	ALA4377685		%	Homo sapiens
18.	ALA4847460	VIB-MDA-007	INH	=	29	%	ALA4808055		%	Homo sapiens
19.	ALA4855979	VIB-MDA-006	INH	=	51	%	ALA4808055		%	Homo sapiens
20.	ALA4870763	VIB-MDA-005	INH	=	34	%	ALA4808055		%	Homo sapiens