# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | β-Pyrazofurin Trifluoroacetic Acid Salt | Pirazofurin | Ki | = | 6.2 | uM | ALA4220276 | 5.21 | nM | Methanobacterium thermoautotrophicum | ||
2. | 6-Azauridine | 6-azauridine | Ki | = | 11 | uM | ALA4220276 | 4.96 | nM | Methanobacterium thermoautotrophicum | ||
3. | Uridine 5′-monophosphate | 11,UMP | Ki | = | 330 | uM | ALA2183866 | nM | Methanobacterium thermoautotrophicum | |||
4. | Cytidine 5'-monophosphate | cytidine monophosphate | Ki | = | 1200 | uM | ALA2183866 | nM | Methanobacterium thermoautotrophicum | |||
5. | ALA2178721 | 14, CMP-N3-oxide | Ki | = | 11.1 | uM | ALA2183866 | 4.96 | nM | Methanobacterium thermoautotrophicum | ||
6. | ALA2178721 | 14, CMP-N3-oxide | Ratio Ki | = | 100 | ALA2183863 | Methanobacterium thermoautotrophicum | |||||
7. | ALA1765124 | 35, 2'-deoxy-2'-F-6-CN-UMP | INH | 0 | ALA1767487 | tde | % | Methanobacterium thermoautotrophicum | ||||
8. | ALA1765124 | 35, 2'-deoxy-2'-F-6-CN-UMP | Activity | 0 | ALA1767490 | Active | Methanobacterium thermoautotrophicum | |||||
9. | ALA1765126 | 34, 2'-F-6-N3-UMP | Activity | 0 | ALA1767490 | Active | Methanobacterium thermoautotrophicum | |||||
10. | ALA1765123 | 33, 2'-F-6-I-UMP | Activity | 0 | ALA1767490 | Active | Methanobacterium thermoautotrophicum | |||||
11. | ALA1765124 | 35, 2'-deoxy-2'-F-6-CN-UMP | Kinact | = | 2 | /hr | ALA1767487 | /hr | Methanobacterium thermoautotrophicum | |||
12. | ALA1765126 | 34, 2'-F-6-N3-UMP | Kinact | = | 4 | /hr | ALA1767487 | /hr | Methanobacterium thermoautotrophicum | |||
13. | ALA1765125 | 14, 6-N3-UMP | Kinact | = | 612 | /hr | ALA1767487 | /hr | Methanobacterium thermoautotrophicum | |||
14. | ALA1765124 | 35, 2'-deoxy-2'-F-6-CN-UMP | Ki | = | 30 | mM | ALA1767487 | nM | Methanobacterium thermoautotrophicum | |||
15. | ALA1765126 | 34, 2'-F-6-N3-UMP | Ki | = | 1.2 | mM | ALA1767487 | nM | Methanobacterium thermoautotrophicum | |||
16. | ALA1765125 | 14, 6-N3-UMP | Ki | = | 6.3 | 10'-4mM | ALA1767487 | 6.20 | nM | Methanobacterium thermoautotrophicum | ||
17. | ALA1765122 | 37, 2'-deoxy-2'-F-5-CN-UMP | Ki | = | 360 | uM | ALA1767488 | nM | Methanobacterium thermoautotrophicum | |||
18. | ALA1765121 | 36, 2'-deoxy-2'-F-6-CONH2-UMP | Ki | = | 3322 | uM | ALA1767488 | nM | Methanobacterium thermoautotrophicum | |||
19. | ALA1765124 | 35, 2'-deoxy-2'-F-6-CN-UMP | Ki | = | 37 | uM | ALA1767488 | 4.43 | nM | Methanobacterium thermoautotrophicum | ||
20. | ALA1164953 | 8, pyrazofurin-5'-monophosphate | Ki | = | 6.2 | 10'-3mM | ALA1168990 | 5.21 | nM | Methanobacterium thermoautotrophicum |