# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Cyclopamine (ethanol solution) | 1 | INH | 0 | ALA2153872 | Not Active | % | Mus musculus | ||||
2. | ALA2152380 | 29, BRD-6851 | INH | 0 | ALA2153872 | Not Active | % | Mus musculus | ||||
3. | ALA2152376 | 25, BRD-0607 | INH | 0 | ALA2153872 | Not Active | % | Mus musculus | ||||
4. | ALA2152380 | 29, BRD-6851 | INH | 0 | ALA2153871 | Active | % | Mus musculus | ||||
5. | Vismodegib (GDC-0449) | 101, GDC-0449 | INH | 0 | ALA2153870 | Active | % | Mus musculus | ||||
6. | ALA2152380 | 29, BRD-6851 | INH | 0 | ALA2153868 | Active | % | Mus musculus | ||||
7. | ALA2152376 | 25, BRD-0607 | INH | 0 | ALA2153868 | Active | % | Mus musculus | ||||
8. | Vismodegib (GDC-0449) | 101, GDC-0449 | INH | 0 | ALA2153866 | Active | % | Mus musculus | ||||
9. | Cyclopamine (ethanol solution) | 1 | INH | 0 | ALA2153865 | Active | % | Mus musculus | ||||
10. | Cyclopamine (ethanol solution) | 1 | INH | 0 | ALA2155384 | Not Active | % | Mus musculus | ||||
11. | ALA2152380 | 29, BRD-6851 | INH | 0 | ALA2155384 | Not Active | % | Mus musculus | ||||
12. | ALA2152376 | 25, BRD-0607 | INH | 0 | ALA2155384 | Not Active | % | Mus musculus | ||||
13. | Cyclopamine (ethanol solution) | 1 | IC50 | = | 1.9 | uM | ALA2155383 | 5.72 | nM | Mus musculus | ||
14. | ALA2152380 | 29, BRD-6851 | IC50 | = | 2 | uM | ALA2155383 | 5.70 | nM | Mus musculus | ||
15. | ALA2152376 | 25, BRD-0607 | IC50 | = | 8.1 | uM | ALA2155383 | 5.09 | nM | Mus musculus | ||
16. | Cyclopamine (ethanol solution) | 1 | IC50 | = | 1.5 | uM | ALA2155382 | 5.82 | nM | Mus musculus | ||
17. | ALA2152380 | 29, BRD-6851 | IC50 | = | 3.5 | uM | ALA2155382 | 5.46 | nM | Mus musculus | ||
18. | ALA2152376 | 25, BRD-0607 | IC50 | = | 8.8 | uM | ALA2155382 | 5.06 | nM | Mus musculus | ||
19. | ALA2152380 | 29, BRD-6851 | Ratio IC50 | = | 32 | ALA2153873 | Mus musculus | |||||
20. | ALA2152376 | 25, BRD-0607 | Ratio IC50 | = | 18 | ALA2153873 | Mus musculus |