# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | vaborbactam | 27, RPX7009 | MIC | <= | 0.06 | ug ml-1 | ALA3579496 | ug.mL-1 | Klebsiella pneumoniae | |||
2. | vaborbactam | 27, RPX7009 | MIC | = | 0.13 | ug ml-1 | ALA3579493 | ug.mL-1 | Klebsiella pneumoniae | |||
3. | vaborbactam | 27, RPX7009 | MIC | <= | 0.06 | ug ml-1 | ALA3578635 | ug.mL-1 | Klebsiella pneumoniae | |||
4. | vaborbactam | 27, RPX7009 | MIC | = | 0.25 | ug ml-1 | ALA3578627 | ug.mL-1 | Klebsiella pneumoniae | |||
5. | clavulanic acid | Clavulanic acid | IC50 | = | 10.5 | uM | ALA1218087 | 4.98 | nM | Klebsiella pneumoniae | ||
6. | tazobactam | 2 Tazobactam | IC50 | = | 0.37 | uM | ALA1218087 | 6.43 | nM | Klebsiella pneumoniae | ||
7. | Meropenem | 3 | Activity | = | 37 | % | ALA1217955 | % | Klebsiella pneumoniae | |||
8. | Meropenem | 3 | Activity | = | 0.92 | % | ALA1217940 | % | Klebsiella pneumoniae | |||
9. | Imipenem | Imipenem | Activity | = | 45 | % | ALA1217955 | % | Klebsiella pneumoniae | |||
10. | Imipenem | Imipenem | Activity | = | 7.9 | % | ALA1217940 | % | Klebsiella pneumoniae | |||
11. | Doripenem | Doripenem | Activity | = | 45 | % | ALA1217955 | % | Klebsiella pneumoniae | |||
12. | Doripenem | Doripenem | Activity | = | 0.14 | % | ALA1217940 | % | Klebsiella pneumoniae | |||
13. | Ceftazidime | CAZ | Activity | = | 0.22 | % | ALA1217955 | % | Klebsiella pneumoniae | |||
14. | Ceftazidime | CAZ | Activity | = | 0.097 | % | ALA1217940 | % | Klebsiella pneumoniae | |||
15. | penicillin G | Benzylpenicillin | Activity | = | 260 | % | ALA1217955 | % | Klebsiella pneumoniae | |||
16. | penicillin G | Benzylpenicillin | Activity | = | 15 | % | ALA1217940 | % | Klebsiella pneumoniae | |||
17. | Ceftazidime | CAZ | Kcat/Km | = | 0.002 | /s/microM | ALA1217925 | /s/microM | Klebsiella pneumoniae | |||
18. | Doripenem | Doripenem | Kcat/Km | = | 0.34 | /s/microM | ALA1217925 | /s/microM | Klebsiella pneumoniae | |||
19. | Meropenem | 3 | Kcat/Km | = | 0.28 | /s/microM | ALA1217925 | /s/microM | Klebsiella pneumoniae | |||
20. | Imipenem | Imipenem | Kcat/Km | = | 0.34 | /s/microM | ALA1217925 | /s/microM | Klebsiella pneumoniae |