# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | vaborbactam | 27, RPX7009 | MIC | <= | 0.06 | ug ml-1 | ALA3579496 | ug.mL-1 | Klebsiella pneumoniae | |||
2. | vaborbactam | 27, RPX7009 | MIC | = | 0.13 | ug ml-1 | ALA3579493 | ug.mL-1 | Klebsiella pneumoniae | |||
3. | vaborbactam | 27, RPX7009 | MIC | <= | 0.06 | ug ml-1 | ALA3578635 | ug.mL-1 | Klebsiella pneumoniae | |||
4. | vaborbactam | 27, RPX7009 | MIC | = | 0.25 | ug ml-1 | ALA3578627 | ug.mL-1 | Klebsiella pneumoniae | |||
5. | Meropenem | 3 | Activity | = | 64 | % | ALA1659697 | % | Klebsiella pneumoniae | |||
6. | Meropenem | 3 | Activity | = | 57 | % | ALA1659695 | % | Klebsiella pneumoniae | |||
7. | Meropenem | 3 | Activity | < | 2 | % | ALA1659694 | % | Klebsiella pneumoniae | |||
8. | Meropenem | 3 | Activity | = | 76 | U | ALA1659689 | U | Klebsiella pneumoniae | |||
9. | Meropenem | 3 | Activity | = | 55 | U | ALA1659687 | U | Klebsiella pneumoniae | |||
10. | Meropenem | 3 | Activity | = | 31 | U | ALA1659686 | U | Klebsiella pneumoniae | |||
11. | Tazobactam acid | 2 Tazobactam | Ki | = | 74 | uM | ALA1639005 | 4.13 | nM | Klebsiella pneumoniae | ||
12. | Sulbactam | 1 | Ki | = | 167 | uM | ALA1639005 | nM | Klebsiella pneumoniae | |||
13. | clavulanic acid | Clavulanic acid | Ki | = | 11 | uM | ALA1639005 | 4.96 | nM | Klebsiella pneumoniae | ||
14. | Nitrocefin | nitrocefin | Kcat | = | 52 | /s | ALA1640979 | /s | Klebsiella pneumoniae | |||
15. | Imipenem | Imipenem | Kcat | = | 19 | /s | ALA1640979 | /s | Klebsiella pneumoniae | |||
16. | Cefotaxime acid | cefotaxime | Kcat | = | 142 | /s | ALA1640979 | /s | Klebsiella pneumoniae | |||
17. | ALA617 | Cephalothin | Kcat | = | 44 | /s | ALA1640979 | /s | Klebsiella pneumoniae | |||
18. | Piperacillin | Piperacillin | Kcat | = | 51 | /s | ALA1640979 | /s | Klebsiella pneumoniae | |||
19. | Nitrocefin | nitrocefin | Kcat/Km | = | 8.7 | /uM/s | ALA1638997 | /uM/s | Klebsiella pneumoniae | |||
20. | Nitrocefin | nitrocefin | Km | = | 6 | uM | ALA1640979 | nM | Klebsiella pneumoniae |